… network of interest. Next, we review the mathematical approaches that are used to model
signaling network … which computational modeling of a signaling network has led to new insights …

… signaling networks convey information in vertebrates, we developed high-throughput LUMIER
to systematically map PPIs in mammalian … Flag-tagged partners in mammalian cells. Their …

… Here we review the organization of the circadian signaling network and the synchronization
mechanisms of the circadian timekeeping system (see Box 1 and Fig. 2 for definitions of …

The innate immune system is the first line of defense against pathogens, which is initiated
by the recognition of pathogen-associated molecular patterns (PAMPs) and endogenous …

… absolute changes in extracellular signals enables cells to make … mammalian signaling
networks store the memories of past stimuli and subsequently use them to compute relative signals…

… In this minireview, we present an emerging view of the signaling network underlying mTOR
regulation of myogenesis, which contrasts with the well established mechanisms in the …

The following collection of reviews concerning Rho GTPases was elaborated in the
perspective of a special anniversary. 30 years ago, Pascal Madaule, postdoc in Richard Axel’s …

The remarkable capacity for pluripotency and self-renewal in embryonic stem cells (ESCs)
requires a finely tuned transcriptional circuitry wherein the pathways and genes that initiate …

… To the best of our knowledge, this particular feature of the mammalian signaling network has
not yet been reported, although this observation is in agreement with the general functional …

… review, we collect the evidence for specific signaling functions of typical 2-Cys Prxs with low
K m for H 2 O 2 and discuss its implication as a conceptually new hub in signaling networks. …