… pathway of inflammation—the p38 mitogen-activated protein kinases (p38MAPK). The signalling
pathway is … Other papers have previously described the other two MAPK pathways, ERK …

… From a functional perspective the SAPK/MAPK signaling pathway is … Complete activation of
SAPK/MAPK signaling generally is … -independent SAPK/MAPK activation can also occur [80]. …

… therapeutic armamentarium for rheumatoid arthritis. Nevertheless, … involved in signal
transduction pathways, most notably … transduction pathways, ie the TRAF/IκBK/NF-κB, MAPK, PI3 …

… Rheumatoid arthritis (RA) is a chronic autoimmune disease in which imbalances in pro-
and anti-inflammatory cytokines promote the induction of autoimmunity, inflammation and joint …

… pathways have been implicated in rheumatoid arthritis, and … kinase and NF-kB pathways
have been designed and are … the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis …

… The blockade of TNF-α, IL-1β, MMP-1, MMP-3, IL-6, and IL-8 by p38 inhibitors suggests
that the main role of the p38 MAPK pathway may be to regulate the IL-17 signal transduction …

… the complexities of the p38 pathway and its many levels of communication with other cellular
signaling pathways. In this review we look at the p38 MAPK pathway from a slightly different …

… MAP kinase pathways. Complex parallel and interlocking signalling cascades link the three
main MAP kinase … Even the extraordinarily complex MAP kinase pathways can now be …

… , and invasion or promote FLSs apoptosis via blocking NF-κB and MAPK pathways. In this
study, a classic model, adjuvant-induced arthritis (AIA) rats, was constructed to investigate the …

… MAP kinase pathways include the ERK pathway, the JNK/SAPK pathway, and the p38
pathway… Moreover, all 3 of the MAP kinase pathways are activated in RA synovium (26). There is …