Compartmentalised MAPK pathways
MD Brown, DB Sacks - Protein-protein interactions as new drug targets, 2008 - Springer
… The mitogen-activated protein kinase (MAPK) pathway provides cells with the means to … of
MAPK signalling, cells can control their responses to the multiple activators of the pathway. In …
MAPK signalling, cells can control their responses to the multiple activators of the pathway. In …
The role of Nrf2 and MAPK pathways in PFOS-induced oxidative stress in zebrafish embryos
… on the MAPK pathway, we also examined the effects of SFN treatment on MAPK gene
expression. … To evaluate the role of MAPK pathways in the regulation of HO-1 responses, we used …
expression. … To evaluate the role of MAPK pathways in the regulation of HO-1 responses, we used …
[HTML][HTML] Map kinase signaling pathways and hematologic malignancies
LC Platanias - Blood, 2003 - Elsevier
… Dual roles for Map kinase pathways in the induction of cytokine responses. Regulation of
cytokine production and participation in cytokine-dependent signaling cascades. …
cytokine production and participation in cytokine-dependent signaling cascades. …
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
K Arimoto, H Fukuda, S Imajoh-Ohmi, H Saito… - Nature cell …, 2008 - nature.com
… JNK MAPK (SAPK) pathways. A functional relationship between the SG and SAPK responses
… Here, we report that SG formation negatively regulates the SAPK apoptotic response, and …
… Here, we report that SG formation negatively regulates the SAPK apoptotic response, and …
A Single MAPKKK Regulates the Hog1 MAPK Pathway in the Pathogenic Fungus Candida albicans
J Cheetham, DA Smith, A da Silva Dantas… - Molecular biology of …, 2007 - Am Soc Cell Biol
… Furthermore, the role of the stress-responsive MAPK pathways in mediating core
transcriptional responses to stress is different in C. albicans (Enjalbert et al., 2006), S. cerevisiae (…
transcriptional responses to stress is different in C. albicans (Enjalbert et al., 2006), S. cerevisiae (…
Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells
S Sengul, C Zwizinski… - American Journal of …, 2003 - journals.physiology.org
… Here, we examined the role of MAPK pathways in these responses using four species of
myeloma LCs (κ 1 , κ 2 , κ 3 , and λ 1 ) previously shown to induce cytokine production by PTCs. …
myeloma LCs (κ 1 , κ 2 , κ 3 , and λ 1 ) previously shown to induce cytokine production by PTCs. …
Targeting MAPK pathway in melanoma therapy
Y Cheng, G Zhang, G Li - Cancer and Metastasis Reviews, 2013 - Springer
… (MAPK) pathway have generated striking clinical response in … , therapies targeting the MAPK
pathway have been proven … specific molecules in MAPK pathway. Although selective BRAF …
pathway have been proven … specific molecules in MAPK pathway. Although selective BRAF …
Differential regulation and properties of MAPKs
M Raman, W Chen, MH Cobb - Oncogene, 2007 - nature.com
… MAPK cascades consist of a … pathway, these enzymes are capable of responding to a
bewildering number of stimuli to produce exquisitely specific cellular outcomes. These responses …
bewildering number of stimuli to produce exquisitely specific cellular outcomes. These responses …
IL-17 stimulates inflammatory responses via NF-κB and MAP kinase pathways in human colonic myofibroblasts
K Hata, A Andoh, M Shimada… - American Journal …, 2002 - journals.physiology.org
… p38 MAPKs as early as 15 min after stimulation. These results indicate that MAPK pathways
… Phosphorylation of the MAPKs was actually blocked by MAPK inhibitors in these cells (Fig. …
… Phosphorylation of the MAPKs was actually blocked by MAPK inhibitors in these cells (Fig. …
[HTML][HTML] Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways
X Chen, W Ma, Y Yao, Q Zhang, J Li, X Wu, C Mei… - Cell death & …, 2021 - nature.com
… , because it promoted apoptosis by activating ASK1-JNK/p38 MAPK pathways in HCC. … then
leaded to activation of the JNK/P38 MAPK pathways. The finding provided a novel antitumor …
leaded to activation of the JNK/P38 MAPK pathways. The finding provided a novel antitumor …