When mast cells are activated they can respond by releasing their secretory granule compounds,
including mast cell-specific proteases of chymase, tryptase and carboxypeptidase A (…

… as compared to the MCT cells were very similar (Table 11). As previously reported for … mast
cells (1 8), carboxypeptidase-positive mast cells were almost the exclusive type of mast cell …

… carboxypeptidase activity was recently identified in highly purified human lung mast cells
and dispersed mast cells … inhibitor as ligand, mast cell carboxypeptidase was purified to …

… carboxypeptidase A mRNA which is transcribed from a single gene. We conclude that mouse
mast cell carboxypeptidase A is a prominent secretory granule enzyme of mast cells of the …

… a carboxypeptidase activity in mast cells from human lung and in dispersed mast cell … The
enzyme activity was detected in a preparation of dispersed human mast cells from lung of >99…

… No gene for a hematopoietic cell carboxypeptidase has previously been characterized.
Mast cell carboxypeptidase A (MCCPA) is a prominent secretory granule marker of mast cell …

… mast cell proteases in Ang II production by using two different mouse strains lacking mast cell
heparin or mouse mast cell … Ang I was added to ex vivo cultures of peritoneal cells, and the …

… Mc-cpa is the only enzyme with carboxypeptidase specificity expressed in mast cells. Lysates
from Mc-cpa +/+ , Mc-cpa + / − , and Mc-cpa − / − peritoneal cells were incubated with test …

… presence of carboxypeptidases B1 or A2 in mast cells (Figure 6… localization of pancreatic
carboxypeptidases and tryptase only … In addition, cells containing pancreatic carboxypeptidases …

… carboxypeptidase was reported in mast cells and mast cell containing tissues [2-41. The
carboxypeptidase … it was rapidly degraded by the mast cell chymotrypsin 121. In general, these …