[HTML][HTML] Immune response to snake envenoming and treatment with antivenom; complement activation, cytokine production and mast cell degranulation

SF Stone, GK Isbister, S Shahmy… - PLoS neglected …, 2013 - journals.plos.org
Snake bite is one of the most neglected public health issues in poor rural communities
worldwide. In addition to the clinical effects of envenoming, treatment with antivenom frequently …

[HTML][HTML] Human mast cell tryptase is a potential treatment for snakebite envenoming across multiple snake species

E Anderson, K Stavenhagen, D Kolarich… - Frontiers in …, 2018 - frontiersin.org
… the World Health Organization has recently reinstated snakebite envenoming to its list of …
mast cell proteases to detoxify six venoms from a spectrum of phylogenetically distinct snakes. …

[HTML][HTML] Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators …

NG Nascimento, MC Sampaio, RA Olivo, C Teixeira - Toxicon, 2010 - Elsevier
… In the case of Bothrops moojeni snake, responsible for most snake poisonings in the region
… When compared to Bothrops jararaca snake bites, the most common accident in Brazil, B. …

[HTML][HTML] Mast cells and IgE can enhance survival during innate and acquired host responses to venoms

SJ Galli, P Starkl, T Marichal, M Tsai - Transactions of the American …, 2017 - ncbi.nlm.nih.gov
… However, because of the considerations noted, including the possibility of needing to treat
an anaphylactoid or anaphylactic reaction to CroFab ® , I think that transporting a snake bite

Mast cells and IgE in defense against venoms: possible “good side” of allergy?

SJ Galli, P Starkl, T Marichal, M Tsai - Allergology international, 2016 - jstage.jst.go.jp
… 5e7,12,13 Basophils activated via Fc 3 RI aggregation can release a panel of mediators
partially overlapping with those of mast cells, but, as compared to mast cells, they contain much …

Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin

LA Schneider, SM Schlenner, TB Feyerabend… - The Journal of …, 2007 - rupress.org
… We conclude that mast cells attack ET and sarafotoxin exactly at the structure … Mast cells
have crucial functions in innate immunity. A protective role of mast cells is evident in mast cell–…

Mast cells can enhance resistance to snake and honeybee venoms

M Metz, AM Piliponsky, CC Chen, V Lammel… - Science, 2006 - science.org
… Although intraperitoneal injection has been recommended for analyses of the systemic
toxicity of snake venoms (4), many snake bites are to the skin and subcutaneous tissue. MC-…

Edema formation and degranulation of mast cells by Trimeresurus mucrosquamatus snake venom

J Chen, HF Chiu, HT Huang, CM Teng - Toxicon, 1984 - Elsevier
… Edema formation and degranulation of mast cells by … and degranulation of mesentery mast
cells with a decreased electron density … It is concluded that histamine released from mast cells

[PDF][PDF] The role of mast cells in non-allergic inflammation

A Weissler, YA Mekori, A Mor - The Israel Medical Association …, 2008 - researchgate.net
Snake bites and bee stings For many years MCs were believed to contribute to the
complications caused by snake bites and bee stings through the release of tissue-damaging …

Oedema formation and degranulation of mast cells by phospholipase A2 purified from porcine pancreas and snake venoms

S Lloret, JJ Moreno - Toxicon, 1993 - Elsevier
… on mast cell membranes prelabelled with [3H] arachidonic acid was determined, a relationship
between the enzymatic activity and mast cell … activity on mast cell membranes, mast cell