Contribution of mast cells and snake venom metalloproteinases to the hyperalgesia induced by Bothrops jararaca venom in rats

AGC Bonavita, AS Da Costa, ALA Pires… - Toxicon, 2006 - Elsevier
… inhibitors 1,10-phenantroline and DM43 inhibited mast cell degranulation in … Altogether, our
findings indicate that mast cells seem to … on the ability of the Bjv to activate directly mast cells. …

Potent histamine-releasing activity of atrahagin, a novel snake venom metalloproteinase

JF Wei, YZ Mo, LY Qiao, XL Wei, HQ Chen… - … of Biochemistry & Cell …, 2006 - Elsevier
metalloproteinase were able to activate mast cells. The maximum release of histamine from
colon and lung mast cells occurred at 12 min (8 min for tonsil mast cells) … on mast cells was …

[HTML][HTML] Inflammatory effects of snake venom metalloproteinases

CFP Teixeira, CM Fernandes, JP Zuliani… - Memórias do Instituto …, 2005 - SciELO Brasil
… mammalian matrix metalloproteinases (MMP) and members of ADAMs (a disintegrin and
metalloproteinase) group. Besides hemorrhage, snake venom metalloproteinase induce local …

[HTML][HTML] Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators …

NG Nascimento, MC Sampaio, RA Olivo, C Teixeira - Toxicon, 2010 - Elsevier
Mast cell degranulation was expressed as the proportion (as %) of mast cells with extruded
granules relative to the total mast cells present in the stained mesentery (250× magnification)…

Inflammatory mediators involved in the paw edema and hyperalgesia induced by Batroxase, a metalloproteinase isolated from Bothrops atrox snake venom

LGB De Toni, DL Menaldo, ACO Cintra… - International …, 2015 - Elsevier
… inflammatory mechanisms induced by snake venom metalloproteinases as well as the … cells
to release mediators that activate mast cells. Mast cells are granulated resident immune cells

Mast cell proteases

G Pejler, M Åbrink, M Ringvall, S Wernersson - Advances in immunology, 2007 - Elsevier
Mast cells (MCs) are traditionally thought of as a nuisance for its host, for example, by …
insults such as bacteria, parasites, and snake venom toxins. When the MC is challenged by an …

Evaluation of the local inflammatory events induced by BpirMP, a metalloproteinase from Bothrops pirajai venom

CP Bernardes, DL Menaldo, CCN Mamede… - Molecular …, 2015 - Elsevier
… , sodium cromoglycate, a mast cell degranulation inhibitor and … inflammation mediated by
mast cell degranulation, histamine… The snake venom metalloproteinases (SVMPs) are divided …

[HTML][HTML] Human mast cell tryptase is a potential treatment for snakebite envenoming across multiple snake species

E Anderson, K Stavenhagen, D Kolarich… - Frontiers in …, 2018 - frontiersin.org
snake venom or snake venom components (13, 29), we hypothesized that the observed
detoxification of red spitting cobra venom by … acid oxidase and a zinc metalloproteinase. l-amino …

An overview of the immune modulating effects of enzymatic toxins from snake venoms

SM Burin, DL Menaldo, SV Sampaio, FG Frantz… - International journal of …, 2018 - Elsevier
Snake venom metalloproteinases (SVMPs) belong to a subclass of zinc-dependent … 1
depicts the effect of snake venom PLA 2 s in mast cell activation and the consequent release of …

Mast cells and IgE in defense against venoms: possible “good side” of allergy?

SJ Galli, P Starkl, T Marichal, M Tsai - Allergology international, 2016 - jstage.jst.go.jp
… Moreover, type 2 immune responses induced by a single exposure to honeybee venom
or Russell's viper venom, which “arm” mast cells with IgE antibodies that bear specificity for …