Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin

LA Schneider, SM Schlenner, TB Feyerabend… - The Journal of …, 2007 - rupress.org
Mast cells are protective against snake venommast cell carboxypeptidase A (Mc-cpa)
activity. Using this mutant, we have now identified Mc-cpa as the essential protective mast cell

Mast cells can enhance resistance to snake and honeybee venoms

M Metz, AM Piliponsky, CC Chen, V Lammel… - Science, 2006 - science.org
… The mechanisms by which snake envenomation can … components of snake venoms can
induce mammalian mast cells (… of venom components, and death associated with snake

[HTML][HTML] Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators …

NG Nascimento, MC Sampaio, RA Olivo, C Teixeira - Toxicon, 2010 - Elsevier
venom (BmV) to induce oedema in mice, the involvement of principal inflammatory mediators
and mast cells … with a peak between 30 and 60 min after venom injection (0.3–1 μg/paw), …

[HTML][HTML] Immune response to snake envenoming and treatment with antivenom; complement activation, cytokine production and mast cell degranulation

SF Stone, GK Isbister, S Shahmy… - PLoS neglected …, 2013 - journals.plos.org
… that IgG aggregates can activate mast cells [34], and … mast cells and this effect is enhanced
in the presence of C3a [36]. It is therefore plausible that the immune response to snake venom

Mast cells and IgE in defense against venoms: possible “good side” of allergy?

SJ Galli, P Starkl, T Marichal, M Tsai - Allergology international, 2016 - jstage.jst.go.jp
… that mast cells can enhance innate resistance to reptile or arthropod venoms during a first
exposure to such venoms… can limit snake venom toxicity. J Allergy Clin Immunol. In press (Ref. …

Edema formation and degranulation of mast cells by Trimeresurus mucrosquamatus snake venom

J Chen, HF Chiu, HT Huang, CM Teng - Toxicon, 1984 - Elsevier
… Histamine released from mast cells could be assayed spectrophotofluometrically. The
antagonism by diphenhydramine of venom-induced histamine release from mast cells was …

Contribution of mast cells and snake venom metalloproteinases to the hyperalgesia induced by Bothrops jararaca venom in rats

AGC Bonavita, AS Da Costa, ALA Pires… - Toxicon, 2006 - Elsevier
… -phenantroline and DM43 inhibited mast cell degranulation in vitro, under … Altogether, our
findings indicate that mast cells seem to … on the ability of the Bjv to activate directly mast cells. …

IgE and mast cells in host defense against parasites and venoms

K Mukai, M Tsai, P Starkl, T Marichal… - Seminars in …, 2016 - Springer
snake venoms puts them at risk for having a potentially fatal anaphylactic reaction upon
subsequent exposure to such venoms. … responses associated with mast cell activation and IgE is …

[HTML][HTML] Mast cells and IgE can enhance survival during innate and acquired host responses to venoms

SJ Galli, P Starkl, T Marichal, M Tsai - Transactions of the American …, 2017 - ncbi.nlm.nih.gov
… local anaphylaxis can limit snake venom toxicity. J Allergy … venoms also can induce mast
cell degranulation in vitro. So, I think that it is very likely that many venoms can induce mast cell

Edema formation and degranulation of mast cells by a basic phospholipase A2 purified from Trimeresurus mucrosquamatus snake venom

HF Chiu, J Chen, CM Teng - Toxicon, 1989 - Elsevier
mast cells by a basic phospholipase A2 purified from Trimeresurus mucrosquamatus snake
venom… ) purified from Trimeresurus mucrosquamatus snake venom was injected into the …