Oedema formation and degranulation of mast cells by phospholipase A2 purified from porcine pancreas and snake venoms

S Lloret, JJ Moreno - Toxicon, 1993 - Elsevier
… little or no degranulation of the mast cells (HINES et al., 1972… PLAZ enzymes from snake
venoms and porcine pancreas in … activity on mast cell membranes, mast cell degranulation and …

Mast cells and IgE in defense against lethality of venoms: Possible “benefit” of allergy

SJ Galli, M Metz, P Starkl, T Marichal, M Tsai - Allergo journal international, 2020 - Springer
… of the venoms of six different poisonous snakes [84]. … venom or Russell’s viper venom,
which “arm” mast cells with IgE antibodies that bear specificity for components of those venoms, …

Human mast cell tryptase is a potential treatment for snakebite envenoming across multiple snake species

E Anderson, K Stavenhagen, D Kolarich… - Frontiers in …, 2018 - frontiersin.org
… Based on previous reports by us and others showing that mouse MC proteases are able
to detoxify snake venom or snake venom components (13, 29), we hypothesized that the …

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

M Akahoshi, CH Song, AM Piliponsky… - The Journal of …, 2011 - Am Soc Clin Investig
mast cells can enhance the resistance of mice to the venoms of certain snakes and that mouse
mast cell–… Here, we investigated whether mast cells can enhance resistance to the venom

Testing the 'toxin hypothesis of allergy': mast cells, IgE, and innate and acquired immune responses to venoms

M Tsai, P Starkl, T Marichal, SJ Galli - Current opinion in immunology, 2015 - Elsevier
… The authors found that caspase-1-deficient mice were more susceptible to the toxicity of
bee and snake venoms, suggesting that a caspase-1-dependent innate immune response can …

Bothrops jararacussu snake venom lectin induces mast cell activation and vascular permeability enhance in an animal model

FH Kwasniewski, AM Kayano, AN Fukunaga… - Toxicon, 2022 - Elsevier
… jararacussu snake venom, on mast cells and vasopermeability were investigated in this
study. BjcuL activates mast cells and increases vasopermeability through the involvement of …

Snake venom rhodocytin induces plasma extravasation via toxin-mediated interactions between platelets and mast cells

Y Nakamura, T Sasaki, C Mochizuki, K Ishimaru… - Scientific Reports, 2019 - nature.com
… did not directly stimulate mast cells, and mast cells did not express CLEC-… mast cell activation
by snake venom: some toxins may activate mast cells indirectly, with platelets or other cells

Potent histamine-releasing activity of atrahagin, a novel snake venom metalloproteinase

JF Wei, YZ Mo, LY Qiao, XL Wei, HQ Chen… - … of Biochemistry & Cell …, 2006 - Elsevier
… of human mast cells by … mast cells, which suggested strongly that mast cell degranulation
may play a role in the pathogenesis of snakebite wound. Atrahagin, a novel snake venom

Inflammatory mediators involved in the paw edema and hyperalgesia induced by Batroxase, a metalloproteinase isolated from Bothrops atrox snake venom

LGB De Toni, DL Menaldo, ACO Cintra… - International …, 2015 - Elsevier
… may also act indirectly by stimulating other inflammatory cells to release mediators that
activate mast cells. Mast cells are granulated resident immune cells found close to capillaries that …

Inflammatory effects of snake venom myotoxic phospholipases A2

CFP Teixeira, ECT Landucci, E Antunes, M Chacur… - Toxicon, 2003 - Elsevier
… by exogenously administered snake venom PLA 2 s comprise methods that evaluate
increase in vascular permeability (mostly paw and skin oedema) and in vitro mast cell histamine …