Mechanism of release from mast cells

B Uvnäs - Chemotherapy, 1961 - karger.com
… of strongly hemolytic snake venoms has led to the “lysolecithine” theory, according to which
the active principle is lysolecithine formed in the tissue by the lecithinase A in the venom (4). …

[HTML][HTML] Mast cells as protectors of health

A Dudeck, M Köberle, O Goldmann, N Meyer… - Journal of Allergy and …, 2019 - Elsevier
… and elimination of toxins or venoms. MCs can enhance … Uterine tissue remodeling by α-chymase
(mast cell protease [… detoxify an increasing number of venoms and endogenous toxins. …

Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A2

JF Wei, XL Wei, YZ Mo, SH He - BMC immunology, 2009 - Springer
… found that mast cells can be activated by snake venom and … that snake venom PLA 2 could
induce mast cell accumulation … a mast cell-specific effect since the relative number of mast

Mast cell degranulation induced by two phospholipase A2 homologues: dissociation between enzymatic and biological activities

ECT Landucci, RC Castro, MF Pereira… - European Journal of …, 1998 - Elsevier
… Bothropstoxin-I and bothropstoxin-II are phospholipase A 2 homologues isolated from
Bothrops jararacussu snake venom. The former is devoid of phospholipase A 2 activity whereas …

Mast cell proteases

G Pejler, M Åbrink, M Ringvall, S Wernersson - Advances in immunology, 2007 - Elsevier
Mast cells (MCs) are traditionally thought of as a nuisance for its host, for example, by …
insults such as bacteria, parasites, and snake venom toxins. When the MC is challenged by an …

The mast cell-IgE paradox: from homeostasis to anaphylaxis

SJ Galli - The American journal of pathology, 2016 - Elsevier
… that mast cells can enhance innate host resistance to reptile or arthropod venoms during …
to a first exposure to the venoms of three species of poisonous snakes, the Gila monster, the …

An overview of the immune modulating effects of enzymatic toxins from snake venoms

SM Burin, DL Menaldo, SV Sampaio, FG Frantz… - International journal of …, 2018 - Elsevier
… 1 depicts the effect of snake venom PLA 2 s in mast cell activation and the consequent
release of histamine and other mediators of inflammation, such as platelet-activating factor (PAF), …

Novel insights into the biological function of mast cell carboxypeptidase A

G Pejler, SD Knight, F Henningsson… - Trends in immunology, 2009 - cell.com
mast cell-specific proteases of chymase, tryptase and carboxypeptidase A (MC-CPA) type.
MC-CPA is a dominant protein component of the mast cell … 1 and snake venom toxins. Here, …

[PDF][PDF] The role of mast cells in non-allergic inflammation

A Weissler, YA Mekori, A Mor - The Israel Medical Association …, 2008 - researchgate.net
… For many years MCs were believed to contribute to the complications caused by snake bites
… against honeybee venom, although it is still unclear if CPA is the major anti-venom agent in …

Studies on a mast cell degranulating factor in bee venom

B Fredholm - Biochemical Pharmacology, 1966 - Elsevier
… and snake venoms containing phosphatidase A are known to cause degranulation of mast
cells … Recent studies have shown that a factor in bee venom, not related to phosphatidase A, …