Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action

C Montecucco, JM Gutiérrez, B Lomonte - Cellular and Molecular Life …, 2008 - Springer
… These toxins are produced by the snake venom gland and, … Thus heparin, if rapidly released
by mast cells upon exposure to … A protective role of mast cell-derived mediators during bee (…

Effect of disodium cromoglycate on phospholipase A activity: Studies with egg yolk and isolated mast cell systems

MC Hines, GF Moss, JSG Cox - Biochemical Pharmacology, 1972 - Elsevier
… Purified snake venom phospholipase A alone did not cause significant … mast cells. Although
phospholipase A and chymotrypsin acted synergistically to release histamine from mast cells

The phylogenetic profile of mast cells

E Crivellato, L Travan, D Ribatti - Mast Cells: Methods and Protocols, 2015 - Springer
Mast cells (MCs) are tissue-based immune cells that participate to both innate and adaptive
immunities as well as to tissue-remodelling processes. Their evolutionary history appears as …

Biochemical and biological properties of phospholipases A2 from Bothrops atrox snake venom

MM Kanashiro, ME Rita de Cássia, JH Petretski… - Biochemical …, 2002 - Elsevier
mast cell degranulation and, in vivo, of causing creatine kinase release, edema, and myonecrosis
typical of PLA 2 s from snake venoms, … of affected skeletal muscle cells. BaPLA 2 I- and …

Evaluation of the local inflammatory events induced by BpirMP, a metalloproteinase from Bothrops pirajai venom

CP Bernardes, DL Menaldo, CCN Mamede… - Molecular …, 2015 - Elsevier
… isolated from Bothrops pirajai snake venom. The animals … sodium cromoglycate, a mast
cell degranulation inhibitor and … inflammation mediated by mast cell degranulation, histamine…

Receptor modulation and mast cell secretion

DC Morrison - Journal of Investigative Dermatology, 1978 - Elsevier
… we have recently isolated from cobra venom (CV A protein) [2]. … mast cell activator in studying
the mechanisms of mast cell … was purified from the venom of Naja naja (Ross Snake Farm, …

The role of mast cells in inflammatory processes: evidence for nerve/mast cell interactions

J Bienenstock, M Tomioka, H Matsuda… - … Archives of Allergy and …, 1987 - karger.com
… seminal plasma from many species, and in various snake venoms. There is greater than
90% homology between murine and human NGF as deduced from genomic sequence data. …

Mast cells in inflammation and disease: recent progress and ongoing concerns

SJ Galli, N Gaudenzio, M Tsai - Annual review of immunology, 2020 - annualreviews.org
… in host defense, ie, promoting resistance to certain venoms, has also been supported both
by work in mast cell–engrafted WBB6F1-Kit W/Wv and C57BL/6-Kit W-sh/W-sh mice and by …

[HTML][HTML] Secreted phospholipase A2 and mast cells

M Murakami, Y Taketomi - Allergology International, 2015 - Elsevier
… Classically, sPLA 2 s have been found abundantly in snake or insect venom. In mammals, …
in allergy, focusing on mast cells (MCs) which occupy a central role in allergic responses. …

Inflammatory events induced by Lys-49 and Asp-49 phospholipases A2 isolated from Bothrops asper snake venom: role of catalytic activity

JP Zuliani, CM Fernandes, SR Zamuner, JM Gutiérrez… - Toxicon, 2005 - Elsevier
… in this study, although it is suggested that peritoneal macrophages and mast cells are likely
to be involved. The effects of both PLA 2 s on these cells are currently being investigated. …