… Moreover, the number of animals surviving 60 min after injection of venom rose from 20
to 60%. Our results demonstrate an important role for mast cells in the … serrulatus venom. …

… To further analyze the effect of Tsv on mast cells, we have quantified 5-HT release from
mesenteric and peritoneal mast cells and evaluated mesenteric mast cell degranulation by …

… cells (Paneque Peres et al., 2009). On the other hand, using rats and a culture … mast
cells, Ts venom caused a remarkable edema in rat airways which are independent of mast cell …

… Tityus serrulatus scorpion venom (Tsv) induces an inflammatory response, just a few have
investigated the effect of the venom … to evaluate alterations of venom application on lymphoid …

… fera); and the scorpion (Tityus serrulatus). In this study we … of the mast cells to the venoms:
a) concentration of the venom; b) … of concentration The lyophilized venoms were diluted in a …

… vascular permeability and to trigger mast cells to release histamine, resulting in vasodilation
and the promotion of chemotaxis (cell movement) of inflammatory cells into the site of injury (…

… of bronchial epithelial cells in the pulmonary effects of Tityus serrulatus scorpion venom (Tsv). …
In the airways, at least macrophages and mast cells can trigger an inflammatory reaction, …

… Complement system activation [20,21], release of substance P [22], activation of mast cells
[23] and subsequent release of other mediators (PAF, leukotrienes and prostaglandins) can …

… There are two likely sources of this autacoid: endogenous release from mast cells or intrinsic
content of the venom. The lack of effect of cromolyn indicates that the exogenous source of …

… cytolytic agent acting on mast cells, through two different … cells: (i) binding to a GPCR related
to the control of mast cell exocytosis and (ii) small structural deorganization of the mast cell …