Analysis of activator and repressor functions reveals the requirements for transcriptional control by LuxR, the master regulator of quorum sensing in Vibrio harveyi

JC van Kessel, LE Ulrich, IB Zhulin, BL Bassler - MBio, 2013 - Am Soc Microbiol
… LuxR-type transcription factors are the master regulators of quorum sensing in vibrios.
LuxR … We find here that unlike TetR proteins, LuxR acts a global regulator, directly binding …

[HTML][HTML] Osteopontin—a master regulator of epithelial-mesenchymal transition

AN Kothari, ML Arffa, V Chang, RH Blackwell… - Journal of clinical …, 2016 - mdpi.com
… OPN is positioned as an upstream and critical regulator of EMT (Figure 2A). … OPN and
many traditional “master regulators” provides evidence that OPN is a major regulator of EMT. …

Metallothionein: the multipurpose protein

P Coyle, JC Philcox, LC Carey, AM Rofe - Cellular and Molecular Life …, 2002 - Springer
… brain isoform, MT-3, has a specific neuronal growth inhibitory activity, while MT-1 and MT-2
has enhance our understanding of the multifaceted role of MT, emphasised in this review. …

[HTML][HTML] Bcl-2 family proteins: master regulators of cell survival

J Hatok, P Racay - Biomolecular concepts, 2016 - degruyter.com
… , proteins of the Bcl-2 family play important roles in regulating other cellular pathways with a
… This review summarizes the recent knowledge about functions of Bcl-2 family proteins that …

The SR protein family of splicing factors: master regulators of gene expression

JC Long, JF Caceres - Biochemical Journal, 2009 - portlandpress.com
… Furthermore, B52/SRp55 regulates the inclusion of alternative exon 2 in eyeless, a master
regulator of eye development in Drosophila, resulting in the production of a protein isoform …

Roles of the metallothionein family of proteins in the central nervous system

J Hidalgo, M Aschner, P Zatta, M Vašák - Brain research bulletin, 2001 - Elsevier
… Mammalian MTs are comprised of four major isoforms designated MT-1 trough MT-4. MT-1
and MT-2 … In this review we will refer exclusively to MT-1, MT-2, MT-3, and MT-4 subfamilies, …

[HTML][HTML] The mechanism of melatonin and its receptor MT2 involved in the development of bovine granulosa cells

S Wang, W Liu, X Pang, S Dai, G Liu - International journal of molecular …, 2018 - mdpi.com
… melatonin and MT2 are essential regulator of bovine GCs function by modulating
reproduction-related genes expression, hormones secretion and other regulators of folliculogenesis. …

IL‐12 and IL‐23: master regulators of innate and adaptive immunity

CL Langrish, BS McKenzie, NJ Wilson… - Immunological …, 2004 - Wiley Online Library
… Together, IL-12 and IL-23 are indeed the master regulators of innate and adaptive immunity.
Much will be gained by re-examining relevant infectious disease models, tumor immunity, …

PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development

C Galinha, H Hofhuis, M Luijten, V Willemsen, I Blilou… - Nature, 2007 - nature.com
… Our gain- and loss-of-function experiments indicate that PLT genes are master switches for
… -2 were crossed to plt1-4;plt2-2 and plt3-1 and allelic combinations were selected from F 2

Induction, regulation, degradation, and biological significance of mammalian metallothioneins

AT Miles, GM Hawksworth, JH Beattie… - Critical reviews in …, 2000 - Taylor & Francis
… the difference between MT-1 and MT2 forms has been attributed to the enhancer activity
in the MT-2a promoter.Furthermore, differential expression of the human MT isoforms can be …