The MT2 melatonin receptor subtype is present in human retina and decreases in Alzheimer's disease

E Savaskan, R Jockers, M Ayoub… - Current Alzheimer …, 2007 - ingentaconnect.com
… Since the histological distribution of the MT2 in human retina is still unknown, the aim of
the present study was to determine the cellular MT2 localization in elderly controls. Also, …

Chemistry and biology of mammalian metallothioneins

M Vašák, G Meloni - JBIC Journal of Biological Inorganic Chemistry, 2011 - Springer
… the brain, in particular of the MT-3 isoform, has … MT-1/MT-2 research till about 1990 and
focus on the recent advances in the structure, chemistry, and biological functions of MT-3 and MT

The regulatory logic of m‐xylene biodegradation by Pseudomonas putida mt2 exposed by dynamic modelling of the principal node Ps/Pr of the TOL plasmid

M Koutinas, MC Lam, A Kiparissides… - Environmental …, 2010 - Wiley Online Library
… is dependent only on the presence of the master regulator. The behaviour of such a system
… of the master regulator of TOL is a common feature of SIMs where the master regulator is …

Nitrogen regulation of the xyl genes of Pseudomonas putida mt2 propagates into a significant effect of nitrate on m‐xylene mineralization in soil

NB Svenningsen, MH Nicolaisen… - Microbial …, 2016 - Wiley Online Library
… The master regulator XylR, encoded by the xylR gene, is transcribed from two σ 70 -dependent
tandem promoters, and is involved in activation of Pu and the σ 54 -dependent Ps1 …

[HTML][HTML] Master transcription factors and mediator establish super-enhancers at key cell identity genes

WA Whyte, DA Orlando, D Hnisz, BJ Abraham, CY Lin… - Cell, 2013 - cell.com
… We report here that the ESC master transcription factors form unusual enhancer domains at
… that are densely occupied by the master regulators and Mediator. Super-enhancers differ …

[PDF][PDF] Melatonin receptors subtypes (MT1 and MT2) in the uterus masculinus of mature male european bison. Biological and seasonal reproductive role

A Tabecka-Lonczynska, J Mytych, P Solek… - J Physiol …, 2018 - jpp.krakow.pl
… of MT1 and MT2 receptors in the uterus masculinus may be of cognitive significance for
mechanisms regulating seasonal reproduction. Differences between MT1 and MT2 expression in …

Protein tyrosine phosphatases–from housekeeping enzymes to master regulators of signal transduction

NK Tonks - The FEBS journal, 2013 - Wiley Online Library
… Overall, I hope that the examples described in this review will illustrate that PTPs are
critical regulators of signalling in their own right, playing an essential role under normal and …

Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance

CW Tam, KW Chan, VWS Liu, B Pang… - Journal of pineal …, 2008 - Wiley Online Library
… The immunohistochemical results of the present study indicated that both MT 1 and MT 2
MLT receptor subtypes are expressed in the basal and secretory epithelium of the human …

Pseudomonas putida mt-2 tolerates reactive oxygen species generated during matric stress by inducing a major oxidative defense response

NB Svenningsen, D Pérez-Pantoja, PI Nikel… - BMC microbiology, 2015 - Springer
… putida mt-2 in the presence of H 2 O 2 (1.5 mM), paraquat (PQ, 100 μM), or without an
oxidative stress inducer (control, Ctrl) as measured by RT-qPCR. Cells were sampled 30 min and …

Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease

G Tosini, S Owino, JL Guillaume, R Jockers - Bioessays, 2014 - Wiley Online Library
… In mammals, pineal melatonin synthesis is under the control of the master circadian … i) recent
advances in MT 1 and MT 2 receptor pharmacology, including MT 1 /MT 2 heteromers and (ii…