[HTML][HTML] PXR interaction with p53: a meeting of two masters

D Robbins, J Bakke, MT Cherian, J Wu, T Chen - Cell death & disease, 2016 - nature.com
… of the master xenobiotic regulator, pregnane X receptor (PXR), on the master regulator of
cell … Thus, the master regulators PXR and p53 appear to have important yet opposing roles in …

Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress

AG Hinnebusch, K Natarajan - Eukaryotic cell, 2002 - Am Soc Microbiol
… This response is complete within 1 to 2 h of the onset of starvation and increases Gcn4p
abundance by a factor of 2 to 10, depending on the strain background. An additional 2-fold …

[HTML][HTML] A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator

PT McGrath, AA Iniesta, KR Ryan, L Shapiro… - Cell, 2006 - cell.com
… Differential activity of the essential cell cycle master regulator CtrA is critical to control of
the G1-S transition. CtrA is a DNA binding response regulator whose activity is controlled by …

Melatonin receptors: molecular pharmacology and signalling in the context of system bias

E Cecon, A Oishi, R Jockers - British journal of pharmacology, 2018 - Wiley Online Library
… of MT 1 and MT 2 receptors, whereas GPR50 will be considered as a regulatory protein that
associates with melatonin receptors. The natural ligand of MT 1 and MT 2 … , MT 1 and MT 2

The p53 tumor suppressor: a master regulator of diverse cellular processes and therapeutic target in cancer

M Farnebo, VJN Bykov, KG Wiman - Biochemical and biophysical research …, 2010 - Elsevier
… However, recent studies have painted a more complex picture of p53 as regulator of diverse
biological processes, such as autophagy, metabolism, and aging [2]. It has been known for …

Neurogenin3: a master regulator of pancreatic islet differentiation and regeneration

JM Rukstalis, JF Habener - Islets, 2009 - Taylor & Francis
… The important role of Ngn3 as a master regulator of endocrine pancreas development directs
attention to finding therapeutic approaches to enhance Ngn3 expression in diabetes as a …

TCF7L2 is a master regulator of insulin production and processing

Y Zhou, SY Park, J Su, K Bailey… - Human molecular …, 2014 - academic.oup.com
… + ] was observed in one Tcf7l2 −/− mouse model, but no major effect on the expression of
Ca 2+ channels (29). Here, we find that although the mRNA levels of several Ca 2+ channels …

[HTML][HTML] FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance

S Zona, L Bella, MJ Burton, GN de Moraes… - Biochimica Et Biophysica …, 2014 - Elsevier
… CENPF, which are under transcriptional control of FOXM1 [2]. Furthermore, there is also
evidence that FOXM1 cooperates with other cell cycle gene regulators, such as B-myb and E2F, …

Melatonin receptors and their regulation: biochemical and structural mechanisms

PA Witt-Enderby, J Bennett, MJ Jarzynka, S Firestine… - Life sciences, 2003 - Elsevier
… and are denoted as MT 1 and MT 2 whereas the newly purified MT 3 protein belongs to the
family of the quinone reductases. The MT 1 and MT 2 melatonin receptors are classified as …

Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast

K Natarajan, MR Meyer, BM Jackson… - … and cellular biology, 2001 - Am Soc Microbiol
… Numerous genes encoding protein kinases and transcription factors were identified as targets,
suggesting that Gcn4p is a master regulator of gene expression. Interestingly, expression …