The transcription factor Nrf2, nuclear factor erythroid-2-related factor 2, activates the transcription
of over 500 genes in the human genome, most of which have cytoprotective functions. …

… to be one or even the master regulator of the balance between cell cycle, differentiation and
apoptosis. By interacting with a variety of proteins, particularly transcription factors, it modu…

… We have also learned a great deal about the mechanisms regulating IKK complex activity;
however, a full understanding of the precise biochemical events and molecular interactions …

… are adipogenic master regulators and are significantly associated with milk fat synthesis in
BMECs.38-41 SCD1 and SREBP1 are the key positive regulators in milk fat synthesis.42, 43 …

… Mammary epithelia lacking Elf5 exhibited downregulation of several other critical genes
involved in alveologenesis, suggesting Elf5 as a master regulator in alveolar development. We …

… As metallothionein (MT) proteins play a major role in metal detoxification, we examined the
expression of MT genes both under noninducing conditions and after exposure to sublethal …

… We conclude that in CSM, opiorphins are master regulators of the hypoxic response. Opiorphin
up-… Fu, S., Tar, MT, Melman, A., Davies, KP Opiorphin is a master regulator of the hypoxic …

… line MT-2 cells were cultured with asbestos for longer than 8 months and the resultant cells
(MT… decreased after long-term exposure of the MT-2 cells to asbestos. In accordance with this …

… In the present study, we found that 4-P-PDOT, a specific inhibitor of MT2 or LUZ, of which
the latter is a non-selective MT1/2 inhibitor, attenuated the anti-inflammatory effects of MLT by …

… Given its diverse roles, we propose that melatonin is a master regulator in plants. … In this
context, it would be more preferable to refer to melatonin as a master regulator, as suggested by …