Stochasticity of TOL plasmid catabolic promoters sets a bimodal expression regime in Pseudomonas putida mt‐2 exposed to m‐xylene

R Silva‐Rocha, V de Lorenzo - Molecular microbiology, 2012 - Wiley Online Library
… Apart from this autonomous regulatory circuit, the TOL network is … The TOL network is also
subject to catabolite repression … In this strain, the XylR regulator is expressed from the TOL

A composite feed-forward loop I4-FFL involving IHF and Crc stabilizes expression of the XylR regulator of Pseudomonas putida mt-2 from growth phase perturbations

R Silva-Rocha, V de Lorenzo - Molecular BioSystems, 2011 - pubs.rsc.org
… the expression of the master regulator of the TOL system (XylR) … TOL regulatory network ie
that IHF, XylR and P u form a canonical I4-FFL motif in which the IHF is the upstream regulator

Regulation of the E. coli csgD gene encoding the master regulator of biofilm formation: Interplay between multiple transcription factors

H Ogasawara, A Kori, K Yamada… - … Symposium on Micro …, 2009 - ieeexplore.ieee.org
… Thus, CsgD is a master regulator of bacterial biofilm formation. Reflecting the response of …
competition between positive and negative regulators but also cooperative interplay within …

A PPARγ-Bnip3 axis couples adipose mitochondrial fusion-fission balance to systemic insulin sensitivity

MJ Tol, R Ottenhoff, M Van Eijk, N Zelcer, J Aten… - Diabetes, 2016 - Am Diabetes Assoc
master regulator and receptor for the thiazolidinedione class of antidiabetic drugs, controls
mitochondrial network … -mediated adipose mitochondrial network fragmentation, improving …

[HTML][HTML] The Small RNA ErsA Impacts the Anaerobic Metabolism of Pseudomonas aeruginosa Through Post-Transcriptional Modulation of the Master Regulator Anr

S Ferrara, R Carrubba, S Santoro… - Frontiers in Microbiology, 2021 - frontiersin.org
… In this work, we expand the knowledge on the regulatory network of ErsA and show its
additional role in the regulation of Anr and consequently of anaerobic metabolism and …

Bacteria as Computers: Formalizing Transcriptional Regulatory Networks by Way of Digital Logic Circuits.

R Silva-Rocha, V de Lorenzo - International Journal of …, 2012 - search.ebscohost.com
… in sub-structures known are network motifs that are endowed with … The first category includes
the so-called master regulators, … To this end, the TOL network and its regulatory wiring were …

Transcriptional kinetics of the cross-talk between the ortho-cleavage and TOL pathways of toluene biodegradation in Pseudomonas putida mt-2

A Tsipa, M Koutinas, EN Pistikopoulos… - Journal of …, 2016 - Elsevier
… Cross talk of the chromosomal and TOL genetic networks … XylR protein activity, the master
regulator of the system, which is … Therefore XylR plays a key role in the TOL regulatory network

“Neural networks” in bacteria: making connections

JP Armitage, IB Holland, U Jenal… - Journal of bacteriology, 2005 - Am Soc Microbiol
… Moreover, transpositional activity of this Tn4652, found in the TOL plasmid, is regulated …
genes by means of differential activation thresholds by the master regulator (d). The single-input …

Information theoretical methods for complex network structure reconstruction

E Hernández-Lemus, JM Siqueiros-García - Complex Adaptive Systems …, 2013 - Springer
… threshold (that we hereon call DPI tol ) -to be determined in a … the most important group
of master regulators in the fruit fly … to have some 50 or more master regulators in its GRN (Costello …

High‐resolution analysis of the m‐xylene/toluene biodegradation subtranscriptome of Pseudomonas putida mt‐2

J Kim, D Pérez‐Pantoja, R Silva‐Rocha… - Environmental …, 2016 - Wiley Online Library
TOL network to gratuitous induction and to 3MBz To complete the picture of the response of
the TOL network … This is a non-metabolizable but strong effector of the master XylR regulator