Maternal antibodies: clinical significance, mechanism of interference with immune responses, and possible vaccination strategies

S Niewiesk - Frontiers in immunology, 2014 - frontiersin.org
… I will review clinical solutions for inhibition of vaccination by maternal antibodies, and the …
mechanism of maternal antibodies. Maternal antibodies inhibit the generation of antibodies

Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries

CE Otero, SN Langel, M Blasi, SR Permar - PLoS pathogens, 2020 - journals.plos.org
mechanisms behind this phenomenon, with a particular focus on the evidence that maternal
antibody (matAb) interference … However, a causal link between maternal humoral immunity …

Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection

SN Langel, CE Otero, DR Martinez, SR Permar - PLoS pathogens, 2020 - journals.plos.org
… , IgA antibodies in breast milk may also contribute to interference of … mechanism to fine-tune
maternal immunizations that maximize infant protection while limiting MatAb interference. …

Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

JEM van der Lubbe, J Vreugdenhil, S Damman… - Virology journal, 2017 - Springer
maternal antibodies can transfer protection against lethal influenza exposure in their offspring.
Subsequently we study whether maternal antibodies interfere … potential mechanisms [51]. …

Immunological interference with the maternal recognition of pregnancy in primates

JP Hearn - Ciba Foundation Symposium 64‐Maternal …, 1979 - Wiley Online Library
… If there are antibodies circulating in levels sufficient to interfere with pregnancy at all, they …
the maternal recognition of pregnancy, but definite proof that it is the recognition mechanism of …

Reciprocal interference of maternal and infant immunization in protection against pertussis

PF Feunou, N Mielcarek, C Locht - Vaccine, 2016 - Elsevier
… with the exception of antibodies to filamentous haemagglutinin (… , where maternal antibodies
were found to interfere with antibody … that interference by maternal antibodies with antibody

The effect of maternal antibodies on the cellular immune response after infant vaccination: a review

MRP Orije, K Maertens, V Corbière, N Wanlapakorn… - Vaccine, 2020 - Elsevier
… (maternal) antibody titers both in animal and human studies. Overall, the findings suggest that
maternally derived antibodies do not interferemechanism and influences of maternal Abs …

Transfer of maternal antibodies results in inhibition of specific immune responses in the offspring

EH CJ - Virus research, 1992 - Elsevier
… might, furthermore, indicate that maternal antibodies interfere with the activation of an immune
… These data indicate that the mechanism(s) of antibody-mediated interference observed in …

Vertically transferred immunity in neonates: mothers, mechanisms and mediators

M Albrecht, PC Arck - Frontiers in Immunology, 2020 - frontiersin.org
… We delineate pathways involved in the transfer of specific maternal antibodies. We also … to
assess the possible interference of maternal antibodies with subsequent infant immunizations (…

Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants

CA Siegrist - Vaccine, 2003 - Elsevier
Several mechanisms have been suggested as mediating the inhibitory influence of
maternal antibodies (MatAb) on infant responses. This inhibition is B cell determinant-specific, …