… We extend previous mathematical models of GC reactions with GC T cells and with the Ag
uptake by centrocytes. This enables us to study the factors controlling the termination of GC …

… Mathematical models based on … in germinal centre reactions and the mechanisms underlying
their clonal selection and cellular differentiation. More recently, mathematical models have …

… We present a mathematical model which reproduces experimental data on the germinal centre
(… By comparing model predictions with experimental results, we propose that the selection …

… occur in the germinal center, a specific part of lymph nodes. We introduce in this article a …
mathematical model of this phenomenon, taking into account the main mechanisms. This model …

… and discrete model, several possible pathways of zone development during germinal center
reactions are investigated. The importance of the zones in the germinal center for affinity …

… We develop mathematical models of (antibody producing) B cells … Mathematically we aim
to model and better predict these signals to gain a deeper understanding of germinal centers …

… Therapeutic interventions on the germinal centers are tantalizing approaches to improve …
build an agent-based model (hyphasma), accounting for the dynamics of the germinal center. It …

… of germinal centres, B-cell migration, selection and differentiation. Mathematical models have
… We argue that mathematical modelling adds a different vantage point to experimental data …

… In this study we focus on the termination of the germinal center reaction, which is still an … for
the control of germinal center dynamics and analyze them through mathematical models. The …

… germinal center cell counts are the average number of concurrent cells, while cells leaving
the germinal center … T cell help is in agreement with previous mathematical models (26) and …