The story of MCF-7 breast cancer cell line: 40 years of experience in research

Ş Comşa, AM Cimpean, M Raica - Anticancer research, 2015 - ar.iiarjournals.org
MCF-7 breast cancer cells are estrogen (E2)-sensitive cells and depend on E2 in order to
proliferate (13). They express high levels of ERα transcripts but low levels of ERβ (14). …

A multidrug resistance transporter from human MCF-7 breast cancer cells

LA Doyle, W Yang, LV Abruzzo… - Proceedings of the …, 1998 - National Acad Sciences
… 7) seen in certain cells that … MCF-7/AdrVp cells. To test this hypothesis, we sought mRNA
species that were differentially overexpressed in MCF-7/AdrVp cells compared with MCF-7 cells

Biological differences among MCF-7 human breast cancer cell lines from different laboratories

CK Osborne, K Hobbs, JM Trent - Breast cancer research and treatment, 1987 - Springer
MCF-7 human breast cancer cells are used widely for studies of tumor biology and … MCF-7
cell lines obtained from different laboratories. MCF-7 (ATCC), MCF-7, MCF-7 (KO), and MCF-7

MCF-7 breast carcinoma cells do not express caspase-3

RU Jänicke - Breast cancer research and treatment, 2009 - Springer
cell lines of varying origin. Curiously, several reports still claim the presence of caspase-3 in
the breast carcinoma cell line MCF-7 … presence of this protease in MCF-7 cells. However, in …

[PDF][PDF] MCF-7: the first hormone-responsive breast cancer cell line

AS Levenson, VC Jordan - Cancer research, 1997 - academia.edu
… to the human ER from MCF-7 breast cancer cells (38). The property of the cells to replicate
… of ER in clinical breast cancer samples, the new laboratory tool would also change the sub …

Differential regulation of growth and invasiveness of MCF-7 breast cancer cells by antiestrogens

EW Thompson, R Reich, TB Shima, A Albini, J Graf… - Cancer Research, 1988 - AACR
… of the estrogen-dependent MCF-7 hu man breast cancer cell line to both proliferate … MCF-7
cells to various antiestrogens, we found that 4-hydroxytamoxifen and tamoxifen inhibited cell

[HTML][HTML] Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells

LM Mooney, KA Al-Sakkaf, BL Brown… - … journal of cancer, 2002 - nature.com
… in breast cancer cells, staurosporine was used as an apoptotic stimulus in the human breast
cancer cell lines MCF-7 and … MCF-7 cells did not express caspase-3, suggesting that DNA …

Effects of antioestrogens on the proliferation of MCF-7 human breast cancer cells

AE Wakeling, E Newboult… - Journal of molecular …, 1989 - jme.bioscientifica.com
breast cancer cells. The … MCF-7 cells. Previous studies have shown that ICI 164384 has a
greater maximal inhibitory effect than conventional antioestrogens on the growth of MCF-7 cells

MCF-7 cells—changing the course of breast cancer research and care for 45 years

AV Lee, S Oesterreich… - … of the National Cancer …, 2015 - academic.oup.com
… line have fundamentally altered the course of breast cancer … of MCF-7 cells to our
understanding of ER action cannot be overstated. We expect that MCF-7 and other breast cancer cell

[HTML][HTML] Effect of insulin on cell cycle progression in MCF-7 breast cancer cells: direct and potentiating influence

J Chappell, JW Leitner, S Solomon… - Journal of Biological …, 2001 - ASBMB
… We recently demonstrated that in MCF-7 breast cancer cells, … to stimulate cell cycle progression
and DNA synthesis in MCF-7 cells. … effect of insulin in MCF-7 cells involves activation of …