Mean platelet volume, thrombocytosis, and survival in non-small cell lung cancer patients treated with first-line pembrolizumab alone or with chemotherapy

M Li, S Zhao, G Lopez, A Secor, P Das, N Surya… - Cancer Immunology …, 2023 - Springer
Platelet function has been linked to both oncogenesis and immune evasion. We studied the
association between the change in mean platelet volume (MPV), platelet count, survival, and …

Mean Platelet Volume to Lymphocyte Ratio: A New Biomarker Predicting Response in Patients with Solid Tumors Treated with Nivolumab

HC Yildirim, F Kus, DC Guven… - Journal of …, 2023 - meridian.allenpress.com
… This study aims to investigate the mean platelet volume to lymphocyte ratio (MPVLR), as
measured by a hemogram test, and median overall survival (mOS) in patients with cancer …

[HTML][HTML] Influence of the Immune Checkpoint Inhibitors on the Hemostatic Potential of Blood Plasma

I Patalakh, A Wandersee, J Schlüter… - Transfusion Medicine …, 2024 - karger.com
… of pembrolizumab, nivolumab, and ipilimumab on platelet aggregation … Perhaps this feature
alone or in combination with other … its special off-target interaction with aggregating platelets. …

Prediction of the therapeutic effects of pembrolizumab and nivolumab in advanced non-small cell lung cancer by platelet-derived microparticles in circulating blood

T Liu, J Wang, Y Liu, J Wu, Y Yuan… - … in Cancer Research …, 2021 - journals.sagepub.com
… Immunotherapy combined with chemotherapy and immunotherapy alone accounted for
76.0% and 24.0% of patients, respectively; of these, 35 (70.0%) patients chose pembrolizumab, …

Basal and one-month differed neutrophil, lymphocyte and platelet values and their ratios strongly predict the efficacy of checkpoint inhibitors immunotherapy in …

M Guida, N Bartolomeo, D Quaresmini… - Journal of translational …, 2022 - Springer
… The anti-PD-1 nivolumab and pembrolizumab, alone or in combination with ipilimumab,
provide higher response rates of approximately 40% and almost 60%, respectively, with the …

Early serum and hematological responses to pembrolizumab therapy as predictors of survival in metastatic urothelial cancer

M Fujiwara, R Fujiwara, T Urasaki, T Oguchi… - Anticancer …, 2022 - ar.iiarjournals.org
… administration of pembrolizumab. Changes in tumor size are commonly used to assess
treatment response and predict patient survival (4). However, changes in tumor size alone do not …

Safety, recommended dose, efficacy and immune correlates for nintedanib in combination with pembrolizumab in patients with advanced cancers

C Baldini, FX Danlos, A Varga, M Texier… - Journal of Experimental …, 2022 - Springer
… delivery) in combination with pembrolizumab (200 mg Q3W, IV). Patients received a 1-week
lead-in dose of nintedanib monotherapy prior starting pembrolizumab. The primary objective …

Role of Hematological Markers in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Treated With Pembrolizumab

K Hagiwara, T Matsuki, T Okada, C Fushimi… - Anticancer …, 2024 - ar.iiarjournals.org
… with pembrolizumab alonepembrolizumab alone. Similar associations were observed with
survival in patients treated with pembrolizumab plus chemotherapy, despite the sample size

Pretreatment clinical and hematologic prognostic factors of metastatic urothelial carcinoma treated with pembrolizumab: a systematic review and meta-analysis

T Yanagisawa, K Mori, S Katayama… - International Journal of …, 2022 - Springer
Pembrolizumab is the standard for the first and second lines in treating metastatic urothelial
carcinoma (UC). This systematic review and meta-analysis aimed to assess the value of …

… value of total tumour volume, adding necrosis to metabolic tumour volume, in advanced or metastatic non-small cell lung cancer treated with first-line pembrolizumab

F Eude, F Guisier, M Salaün, L Thiberville… - Annals of Nuclear …, 2022 - Springer
volume provides a better prognostic determination for NSCLCs treated by pembrolizumab
than metabolic tumour volume alone… III–IV NSCLC with pembrolizumab alone in first line. The …