Mean platelet volume, thrombocytosis, and survival in non-small cell lung cancer patients treated with first-line pembrolizumab alone or with chemotherapy
M Li, S Zhao, G Lopez, A Secor, P Das, N Surya… - Cancer Immunology …, 2023 - Springer
… Platelet function has been linked to both oncogenesis and immune evasion. We studied the
association between the change in mean platelet volume (MPV), platelet count, survival, and …
association between the change in mean platelet volume (MPV), platelet count, survival, and …
Mean Platelet Volume to Lymphocyte Ratio: A New Biomarker Predicting Response in Patients with Solid Tumors Treated with Nivolumab
… This study aims to investigate the mean platelet volume to lymphocyte ratio (MPVLR), as
measured by a hemogram test, and median overall survival (mOS) in patients with cancer …
measured by a hemogram test, and median overall survival (mOS) in patients with cancer …
[HTML][HTML] Influence of the Immune Checkpoint Inhibitors on the Hemostatic Potential of Blood Plasma
I Patalakh, A Wandersee, J Schlüter… - Transfusion Medicine …, 2024 - karger.com
… of pembrolizumab, nivolumab, and ipilimumab on platelet aggregation … Perhaps this feature
alone or in combination with other … its special off-target interaction with aggregating platelets. …
alone or in combination with other … its special off-target interaction with aggregating platelets. …
Prediction of the therapeutic effects of pembrolizumab and nivolumab in advanced non-small cell lung cancer by platelet-derived microparticles in circulating blood
T Liu, J Wang, Y Liu, J Wu, Y Yuan… - … in Cancer Research …, 2021 - journals.sagepub.com
… Immunotherapy combined with chemotherapy and immunotherapy alone accounted for
76.0% and 24.0% of patients, respectively; of these, 35 (70.0%) patients chose pembrolizumab, …
76.0% and 24.0% of patients, respectively; of these, 35 (70.0%) patients chose pembrolizumab, …
Basal and one-month differed neutrophil, lymphocyte and platelet values and their ratios strongly predict the efficacy of checkpoint inhibitors immunotherapy in …
M Guida, N Bartolomeo, D Quaresmini… - Journal of translational …, 2022 - Springer
… The anti-PD-1 nivolumab and pembrolizumab, alone or in combination with ipilimumab,
provide higher response rates of approximately 40% and almost 60%, respectively, with the …
provide higher response rates of approximately 40% and almost 60%, respectively, with the …
Early serum and hematological responses to pembrolizumab therapy as predictors of survival in metastatic urothelial cancer
M Fujiwara, R Fujiwara, T Urasaki, T Oguchi… - Anticancer …, 2022 - ar.iiarjournals.org
… administration of pembrolizumab. Changes in tumor size are commonly used to assess
treatment response and predict patient survival (4). However, changes in tumor size alone do not …
treatment response and predict patient survival (4). However, changes in tumor size alone do not …
Safety, recommended dose, efficacy and immune correlates for nintedanib in combination with pembrolizumab in patients with advanced cancers
C Baldini, FX Danlos, A Varga, M Texier… - Journal of Experimental …, 2022 - Springer
… delivery) in combination with pembrolizumab (200 mg Q3W, IV). Patients received a 1-week
lead-in dose of nintedanib monotherapy prior starting pembrolizumab. The primary objective …
lead-in dose of nintedanib monotherapy prior starting pembrolizumab. The primary objective …
Role of Hematological Markers in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Treated With Pembrolizumab
K Hagiwara, T Matsuki, T Okada, C Fushimi… - Anticancer …, 2024 - ar.iiarjournals.org
… with pembrolizumab alone … pembrolizumab alone. Similar associations were observed with
survival in patients treated with pembrolizumab plus chemotherapy, despite the sample size …
survival in patients treated with pembrolizumab plus chemotherapy, despite the sample size …
Pretreatment clinical and hematologic prognostic factors of metastatic urothelial carcinoma treated with pembrolizumab: a systematic review and meta-analysis
T Yanagisawa, K Mori, S Katayama… - International Journal of …, 2022 - Springer
Pembrolizumab is the standard for the first and second lines in treating metastatic urothelial
carcinoma (UC). This systematic review and meta-analysis aimed to assess the value of …
carcinoma (UC). This systematic review and meta-analysis aimed to assess the value of …
… value of total tumour volume, adding necrosis to metabolic tumour volume, in advanced or metastatic non-small cell lung cancer treated with first-line pembrolizumab
F Eude, F Guisier, M Salaün, L Thiberville… - Annals of Nuclear …, 2022 - Springer
… volume provides a better prognostic determination for NSCLCs treated by pembrolizumab
than metabolic tumour volume alone… III–IV NSCLC with pembrolizumab alone in first line. The …
than metabolic tumour volume alone… III–IV NSCLC with pembrolizumab alone in first line. The …
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