… Our results uncover a descending disynaptic inhibitory circuit that facilitates mechanical
pain, is engaged during stress, and could be targeted to establish higher pain thresholds. …

… whether conditioned pain modulation (CPM) evoked by tonic mechanical stimuli applied to
the … Tonic painful mechanical stimulation was applied to pericranial muscles by a mechanical …

… This research article revealed that RVM GABA-ergic neurons facilitate mechanical pain
through inhibiting GABAergic neurons in the dorsal horn. Descending disynaptic inhibitory …

… In a different study, Hulse et al.50 probed the effect of galanin on mechanical- and cold-pain…
and GalR2 mediates mechanical allodynia.50 Since mechanical- and cold-pain are common …

… defined by their lack of response to noxious tail heat, respond to noxious mechanical
stimulation, suggesting that NEUTRAL cells may represent ON or OFF cell subtypes that respond …

… patients demonstrated evidence of mechanical central sensitization and ineffective CPM
– using tourniquet forearm pain as the conditioning stimulus and mechanical pain as the test …

… Two other studies revealed higher CPM responses for the cold pressor test as compared
to muscle pain, mechanical pain, or tourniquet pain [25,26]. Furthermore, an animal study …

… We can understand endogenous pain modulation as net effect of mechanisms that can
either increase or decrease the experience of pain. WUR is a test that evaluates temporal …

… using heat and mechanical pain reported significant differences in CPM effects between …
differences were detected in pain modulation using temporal summation of pain by Garrett et al. …

… Our main evaluation criterion was mechanical pain threshold. Our secondary criteria were
… mechanical pain threshold after acute stimulation, and no modification of thermal pain …