… response and/or resistance remain elusive, the mechanisms underlying innate (primary) …
novel mechanisms of innate and acquired resistance to immune checkpoint inhibition. …

… mechanisms of resistance to ICIs related to the T-cell activation process and progress in the
development of novel therapies that can overcome resistance. … mechanisms of resistance to …

… Understanding the mechanisms of resistance is thus crucial to this approach of … mechanisms
of resistance to ICIs. Additionally, we explore potential strategies to overcome resistance …

… of immune checkpoints. We also review the known mechanisms of immune checkpoint inhibitors,
… for response and resistance to ICI, and map them to their putative underlying biological …

… clinical utility of ICIs, the mechanisms of resistance to therapy, and local and … resistance.
Although we do not yet fully understand the mechanisms responsible for either form of resistance…

… In this review, we will focus primarily on presumed mechanisms of non-… resistance to immune
checkpoint inhibitors A clinical determination of resistance to immune checkpoint inhibitors (…

… Several resistance mechanisms, such as tumor microenvironment … , resistance mechanisms
against this type of therapy as well as putative therapeutic strategies to overcome resistance …

… Epigenetics studies the nature of mechanisms modifying reversibly, transmissibly (during …
Several epigenetic mechanisms are involved in resistance to the immune checkpoint inhibitors: …

… By elucidating and targeting mechanisms of resistance, treatments can be tailored to …
landscape of immune checkpoint blockade response data, different resistance mechanisms, and …

Marching into the second decade after the approval of ipilimumab, it is clear that immune
checkpoint inhibitors (ICIs) have dramatically improved the prognosis of melanoma. Although …