… inhibitor monotherapy, it is critical to … checkpoint inhibitor monotherapy, and little investigation
of biomarkers to predict responses. By surveying the various mechanisms of resistance …

… In addition, many other immunosuppressive mechanisms … impact on other escape mechanisms
and restores the balance … mechanisms in combination with checkpoint inhibitor blockade …

… Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer over the
… eventually develop resistance. We will review ICI mechanisms of action and resistance. We …

… Here, we will focus more on the most recent evidences in humans of resistance to ICB, and
… mechanisms. For the purpose of this review, we have subdivided mechanisms of resistance …

… Overcoming therapy resistance requires a thorough understanding of the mechanisms … In
this review, we explore the mechanisms of primary and acquired resistance to immunotherapy …

… Lessons from other inhibitors of the RAS pathway suggest … drug resistance, and pre-clinical
studies of G12C inhibitors have … inhibitors, the mechanisms of resistance to G12C inhibitors …

… effort to elucidate the mechanisms of response and resistance to … an update on the mechanisms
of resistance to ICI treatment … In conclusion, immune checkpoint inhibition has proven …

… However, due to primary resistance, approximately 40% of HCC patients do not achieve a
… resistance. This review describes the mechanisms of primary and secondary resistance and …

… Tailoring the specific treatments with distinctive biologic resistance mechanisms would be …
on immune resistance mechanisms, clinical definitions, and management of resistance to ICIs …

… understand the mechanisms underlying efficacy and resistance to PD-1 blockade. … checkpoint
inhibitors in Hodgkin lymphoma The mechanism of action of immune checkpoint inhibitors …