… Lox-1 inhibitors and neutralizing antibodies with promising results in animal models has
made Lox-1 a … In this review, we discuss the main findings regarding the role of Lox-1 in the …

… discuss the biochemistry and genetics of Lox-1 and then go on to describe its tissue expression
and biological role in different cell types. Finally, we will discuss how Lox-1 relates to the …

… Thus, in this study, we simply compare the current results obtained for (8R)-LOX with those
previously obtained for sLOX-1. To the best of our knowledge, the present investigation is the …

… Purified human recombinant 5-LOX (0.5 µg ml −1 PBS pH 7.4 plus 1 mM EDTA) was
preincubated with increasing concentrations of AKBA (blue), NDGA (white) or with vehicle (0.1% …

… and genetics of LOX-1, describe existing evidence supporting the role of LOX-1 in atherogenesis
and its … Induction of angiogenesis may be another mechanism for LOX-1 involvement in …

… An anti-LOX-1 antibody was generated in rabbits against the LOX-1 peptide (residues 188
… acid protein, LOX-1 accession number NP_579840). The 46-amino acid LOX-1 peptide was …

… found in a cluster in chromosome 17p13.1 and murine Alox genes are found in chromosome
… concomitantly enhanced 5-LOX-, but not 15-LOX-, dependent mechanism, which facilitates …

… Using a combination of four custom-made bovine LOX-1–specific constructs (siLOX-1),
we were able to suppress basal and L5-stimulated LOX-1 mRNA in BAECs, whereas the …

… molecule-1 (ICAM-1), LOX-1, and monocyte chemoattractant protein 1 (MCP-1), which
were previously shown to be inducible by oxLDL and therefore served as positive controls. …

… such as LOX 1. A PubMed search was conducted in order to identify relevant articles regarding
LOX-1’… The aim of this review is to investigate LOX-1 role in atherogenesis and explore its …