… since the surge of SARS-CoV-2, almost all mechanistic insights related to molecular and …
SARS-CoV-2 isolates (such as the original Wuhan isolate). Unexpectedly, however, SARS-CoV-…

… The first step of infection with coronaviruses such as severe acute respiratory syndrome
coronavirus (SARS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

… not provide a deeper insight into the molecular mechanism underlying the increased rate of
… We believe that these computational results provide significant mechanistic insights into the …

… first nucleotide of SARS-CoV-2 mRNA. … mechanistic insights into the 2′-O methylation
of the viral mRNA cap. We also discover a distant (25 Å) ligand-binding site unique to SARS-CoV…

… To gain mechanistic insight into the binding of noscapine with the target Mpro enzyme, a
molecular dynamics simulation was performed using the AMBE16 program. (38) The …

… This review presents mechanistic insights and unravels the promise of nitazoxanide as a
repurposed drug candidate for comprehensively addressing COVID-19 pathogenesis. …

… (SARS) marked the worldwide debut of a newly recognized member of the Coronaviridae
viral family, SARS-associated coronavirus (SARS-CoV). … from some animal coronavirus that …

The main proteinase (Mpro), or 3CLpro, is a critical enzyme in the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) lifecycle and is responsible for breaking down and …

… a semimechanistic (ie, partially mechanistic and partially phenomenological) mathematical
model that predicts the whole-body viral distribution kinetics of SARS-CoV-2 by incorporating …

… One of its viral proteins, the SARS coronavirus main protease, is considered as a potential
… atomistic insights into the SARS coronavirus main protease and tries to reveal mechanistic …