[HTML][HTML] Mechanistic Insight into the role of vitamin D and zinc in modulating immunity against COVID-19: A view from an immunological standpoint
… Notably, vitamin D and its derivatives and minerals, such as zinc and magnesium, have …
This comprehensive review aims to provide updated mechanistic details of vitamin D and zinc as …
This comprehensive review aims to provide updated mechanistic details of vitamin D and zinc as …
New insights into the mechanisms of vitamin D action
… Within the DBD two zinc atoms form zinc finger DNA binding motifs (residues 24–90 in the
… may be a major mechanism that couples extracellular signals to vitamin D action. Thus, we …
… may be a major mechanism that couples extracellular signals to vitamin D action. Thus, we …
Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects
S Christakos, P Dhawan, A Verstuyf… - Physiological …, 2016 - journals.physiology.org
… The DBD is a cysteine-rich zinc finger region. There are two zinc fingers, each of which
contains a single zinc atom in a tetrahedral arrangement with four invariant cysteine residues (…
contains a single zinc atom in a tetrahedral arrangement with four invariant cysteine residues (…
Molecular mechanisms of vitamin D action
…, GK Whitfield, I Kaneko, CA Haussler, D Hsieh… - Calcified tissue …, 2013 - Springer
… 1 for kidney, an important mechanism by which the 1,25D/VDR-mediated endocrine or … in
the zinc finger DBD of hVDR [21] confer the phenotype of hereditary hypocalcemic vitamin D-…
the zinc finger DBD of hVDR [21] confer the phenotype of hereditary hypocalcemic vitamin D-…
New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone
MR Haussler, PW Jurutka, JC Hsieh, PD Thompson… - Bone, 1995 - Elsevier
… Weak dimerization is, by analogy with RXR-TR and RXR-RAR, 29 proposed to result
from contact between the D-box in the second zinc finger of RXR and the first zinc finger or …
from contact between the D-box in the second zinc finger of RXR and the first zinc finger or …
A comprehensive mechanistic review insight into the effects of micronutrients on toll-like receptors functions
AH Faghfouri, R Zarrin, V Maleki, L Payahoo… - Pharmacological …, 2020 - Elsevier
… , zinc can regulate TLRs signaling indirectly via the zinc … and as a result additional mechanistic
studies are needed to … its biological effects via combination with Vitamin D receptor (VDR). …
studies are needed to … its biological effects via combination with Vitamin D receptor (VDR). …
Immunomodulatory Effects of Vitamin D and Zinc on Viral Infection
M Rizwan, K Cheng, Y Gang, Y Hou… - Biological Trace Element …, 2024 - Springer
… Vitamin D (VD) and zinc (Zn) have received considerable interest due to their immunomodulatory
properties and ability to enhance the body’s immune defenses. Due to their antiviral, …
properties and ability to enhance the body’s immune defenses. Due to their antiviral, …
[HTML][HTML] Vitamin D metabolism, mechanism of action, and clinical applications
DD Bikle - Chemistry & biology, 2014 - cell.com
… 3 also directly inhibits CYP27B1 expression in the kidney through a complex mechanism
involving VDR and a vitamin D inhibitory receptor (VDIR) that brings both histone deacetylases …
involving VDR and a vitamin D inhibitory receptor (VDIR) that brings both histone deacetylases …
The comprehensive mechanistic insight into the effects of vitamin D on dementia–a review
J Jafarzadeh, L Payahoo, M Yousefi… - Nutrition & Food …, 2022 - emerald.com
… This paper aims to depict the mechanistic role of vitamin D on dementia … mechanistic
role of vitamin D in declining the severity of dementia, keywords including dementia, vitamin D…
role of vitamin D in declining the severity of dementia, keywords including dementia, vitamin D…
New developments in our understanding of vitamin D metabolism, action and treatment
S Christakos, S Li, J De La Cruz, DD Bikle - Metabolism, 2019 - Elsevier
… The modular structure of VDR is comprised of an A/B domain, a conserved zinc finger
DNA-… as an autoregulatory mechanism to prevent hypercalcemia). In addition to 1,25(OH) 2 …
DNA-… as an autoregulatory mechanism to prevent hypercalcemia). In addition to 1,25(OH) 2 …
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