Health effects associated with particulate matter (PM) show seasonal variations. We
hypothesized that these heterogeneous effects may be attributed partly to the differences in the …

… AMs were exposed to both fine inert carbon (CC) or urban complex particles both in vivo
and ex vivo to determine the importance of mediators release from AM on the BM monocyte …

… Increased levels of inflammatory lipid mediators are associated with the inhalation of air
pollution. Oxylipins that promote airway inflammation, including 12,13-DiHOME, 9-HODE, 5-…

… This stimulates cell signaling, transcription factor activation and mediator release in the
respiratory tract, culminating in inflammation. Other postulated mechanisms for asthmatic …

… We further speculated that altered gene-specific methylation would in turn mediate the …
in Shanghai, China, where ambient air pollution levels were much higher than in developed …

… mediate the association between air pollution and adult-onset asthma. We considered
long-term exposure to multiple air pollution … We tested associations between air pollutants and …

… air pollution. A complete understanding of the intricate interactions between air pollution, …
At first, these inflammatory mediators are generated in response to PM 2.5 exposures and …

… The impact of ambient air pollution on excess morbidity and mortality has been well … of air
pollution on respiratory and cardiovascular systems in particular. In addition, air pollution has …

… The proinflammatory effects of PM (represented by red arrows) can be both through direct
PM-cell contact and also through indirect mediator release that can signal to adjacent cells. (…

… Because the lungs are the first organ targeted by inhaled air pollution, it is not surprising
that breathing polluted air is associated with a number of lung diseases, such as chronic …