The efficacy of first-line tyrosine kinase inhibitors combined with co-medications in Asian patients with EGFR mutation non-small cell lung cancer
… use may compromise the clinical efficacy of EGFR-TKIs in … co-medications use in patients
with NSCLC receiving EGFR-TKI … -medications use in NSCLC patients with EGFR mutations in …
with NSCLC receiving EGFR-TKI … -medications use in NSCLC patients with EGFR mutations in …
… of gastric acid-suppressing medication use on the efficacy of erlotinib and gefitinib in patients with advanced non–small-cell lung cancer harboring EGFR mutations
Y Zenke, K Yoh, S Matsumoto, S Umemura, S Niho… - Clinical Lung Cancer, 2016 - Elsevier
… In this study, concurrent use of AS did not … EGFR mutations. It provides data that can guide
expectations for clinicians treating advanced NSCLC patients harboring EGFR mutations with …
expectations for clinicians treating advanced NSCLC patients harboring EGFR mutations with …
Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX …
M Provencio, J Terrasa, P Garrido, RG Campelo… - BMC cancer, 2021 - Springer
… , including the EGFR Thr790Met (T790M) resistance mutation, MET amplification, … EGFR
T790M mutations have been detected in 48–62% of patients that develop resistance to EGFR…
T790M mutations have been detected in 48–62% of patients that develop resistance to EGFR…
Effects of concomitant medication use on gefitinib‐induced hepatotoxicity
S Cho, J Yee, JY Kim, S Jeong Rhie… - The Journal of Clinical …, 2018 - Wiley Online Library
… with EGFR mutations.3, 4 Common toxicities of EGFR TKIs include skin rash, diarrhea, and
nausea, but most are mild in severity and manageable.3, 5 Severe hepatotoxicity involving …
nausea, but most are mild in severity and manageable.3, 5 Severe hepatotoxicity involving …
Polypharmacy among older advanced lung cancer patients taking EGFR tyrosine kinase inhibitors
T Hakozaki, T Matsuo, A Shimizu, Y Ishihara… - Journal of Geriatric …, 2021 - Elsevier
… Potentially inappropriate medication (PIM) use was … analysis to identify factors affecting
multiple-medication use. … is significantly correlated with the BMI, EGFR mutation status, and GRIm-…
multiple-medication use. … is significantly correlated with the BMI, EGFR mutation status, and GRIm-…
FDA- and EMA-Approved Tyrosine Kinase Inhibitors in Advanced EGFR-Mutated Non-Small Cell Lung Cancer: Safety, Tolerability, Plasma Concentration Monitoring …
I Solassol, F Pinguet, X Quantin - Biomolecules, 2019 - mdpi.com
… -TKIs are commonly used together with other types of medication that can substantially interact…
the performance therapy and prognosis of patients with advanced EGFR-mutated NSCLC. …
the performance therapy and prognosis of patients with advanced EGFR-mutated NSCLC. …
[HTML][HTML] Drug-drug interactions, safety, and pharmacokinetics of EGFR tyrosine kinase inhibitors for the treatment of non–small cell lung cancer
CR Kucharczuk, A Ganetsky… - Journal of the Advanced …, 2018 - ncbi.nlm.nih.gov
… For patients whose tumors have sensitizing EGFR mutations, EGFR tyrosine kinase … EGFR
TKIs and can encourage open communication with patients about concurrent medication use …
TKIs and can encourage open communication with patients about concurrent medication use …
Evaluation of Drug—Drug Interactions in EGFR-Mutated Non-Small-Cell Lung Cancer Patients during Treatment with Tyrosine-Kinase Inhibitors
M Occhipinti, M Brambilla, G Galli, S Manglaviti… - Journal of Personalized …, 2021 - mdpi.com
… the possibility to include the list of patient’s medications and to obtain a real-time profile
of … requiring medication, besides anticancer therapies. In addition, patients often use self-…
of … requiring medication, besides anticancer therapies. In addition, patients often use self-…
[HTML][HTML] EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction
… AS are also widely used among the general population as over-the-counter medications
to … We identified patients who tested positive for known sensitizing EGFR mutations (EGFRmut …
to … We identified patients who tested positive for known sensitizing EGFR mutations (EGFRmut …
Therapeutic strategies in EGFR mutant non-small cell lung cancer
HH Loong, SS Kwan, TS Mok, Y Lau - Current treatment options in …, 2018 - Springer
… treatment strategies in EGFR mutation positive NSCLC with a … Combination use of EGFR
TKIs with checkpoint inhibitors is … that required discontinuation of study medications [36•] (Table …
TKIs with checkpoint inhibitors is … that required discontinuation of study medications [36•] (Table …
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