[图书][B] Medicinal chemistry of anticancer drugs

C Avendaño, JC Menéndez - 2015 - books.google.com
… have traditionally represented a main source of cytotoxic anticancer agents.58Nature is a
source of potential chemotherapeutic agents and also of lead compounds that have provided …

Fluorine in medicinal chemistry: A review of anti-cancer agents

C Isanbor, D O'Hagan - Journal of Fluorine Chemistry, 2006 - Elsevier
… In this review those fluorinated compounds which have found a role as anti-cancer agents
are summarized. The emphasis is to highlight the important drugs but also to highlight the …

Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases

MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
… of some targeted anticancer quinazoline derivatives. It … medicinal chemists for supporting
their efforts to design and synthesize novel quinazolines as targeted chemotherapeutic agents

Apoptosis imaging: anti-cancer agents in medicinal chemistry

FG Blankenberg - Anti-Cancer Agents in Medicinal Chemistry  …, 2009 - ingentaconnect.com
There is a rapid expansion in the number of new anti-cancer drugs with remarkably different
mechanisms of action that can augment traditional chemotherapy. As these agents are often …

Nitrogen containing heterocycles as anticancer agents: a medicinal chemistry perspective

A Kumar, AK Singh, H Singh, V Vijayan, D Kumar… - Pharmaceuticals, 2023 - mdpi.com
… The most potent anticancer agent reported in this study was compound 8 with IC 50 values
of 1.17, 1.52, and 417.55 µM against the cell lines HepG-2, MCF-7, and WISH, respectively. It …

Current developments of coumarin-based anti-cancer agents in medicinal chemistry

S Emami, S Dadashpour - European Journal of Medicinal Chemistry, 2015 - Elsevier
… In the efforts to develop suitable anticancer drugs, medicinal chemists have … anticancer
activity. This review article covers the current developments of coumarin-based anticancer agents

Recent advances in the medicinal chemistry of taxoid anticancer agents

I Ojima, SD Kuduk, S Chakravarty - Advances in medicinal chemistry, 1999 - Elsevier
… essential to develop new anticancer agents with fewer side … on the chemistry of paclitaxel
and taxoid anticancer agents at … -generation" taxoid anticancer agents that possess exceptional …

Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents

H Chen, Y Gao, A Wang, X Zhou, Y Zheng… - … of medicinal chemistry, 2015 - Elsevier
… This review summarizes the current progress in medicinal chemistry of UA analogues (Table
3) as potential anticancer agents, which may serve as an important reference for further …

An overview of privileged scaffold: quinolines and isoquinolines in medicinal chemistry as anticancer agents

Y Mao, K Soni, C Sangani, Y Yao - … in Medicinal Chemistry, 2020 - ingentaconnect.com
… Compounds 38 and 39 (Scheme 8) represent potential anticancer agents against the
HeLa cell … inhibitors of Src are being actively investigated as potential anticancer agents [173-175]. …

Acetylenic anticancer agents

A Siddiq, V Dembitsky - … -Cancer Agents in Medicinal Chemistry …, 2008 - ingentaconnect.com
This review is a comprehensive survey of acetylenic anticancer agents obtained from living
organisms. Acetylenic metabolites belong to a class of molecules containing triple bond(s). …