… This leads to tyrosine phosphorylation of numerous proteins, … An inhibitor of the PDGF
receptor tyrosine kinase activity … as epidermal growth factor receptor tyrosine kinase (EGF-RTK) …

… indoles in the design of different tyrosine kinases inhibitors. … of inhibitors against different
tyrosine kinases such as epidermal … based tyrosine kinase inhibitors with improved potency. …

… in quinazoline are appropriate sites for designing new tyrosine kinase inhibitors. This review
should help the medicinal chemist in designing more effective tyrosine kinase inhibitors. …

… abl Tyrosine Kinase - c-abl encodes for a 145 Kd non-receptor tyrosine kinase. Its natural …
which encodes a fusion protein with activated abl tyrosine kinase activity (16). This molecule …

… This report describes the identification, characterization, and SAR analysis of a novel chemical
series of tyrosine kinase inhibitors, 3-substituted indolin-2-ones, which exhibit selectivity …

… , Bruton’s tyrosine Kinase (Btk) has emerged as new target in medicinal chemistry. Since …
, covering advances in the field of medicinal chemistry. Furthermore, the nanoformulations …

The 4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidine PD 158780 is a very potent in vitro
inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC 50 …

… proteinserine/threonine kinases.13,14 However, we … -tyrosine kinase p56Zc* over
protein-serine/threonine kinases.16 … much less active against protein kinase C and protein kinase …

… In so doing, it highlights the importance of medicinal chemistry in all our lives and the
fascination of working in a field which overlaps the disciplines of chemistry, biochemistry, …

… tyrosine kinase signal transduction enzymes,10 containing neighboring binding domains for
both the tyrosine-… of this enzyme are considered to bind to the tyrosine site,7,8,11,12 we and …