Medicinal perspective of indole derivatives: recent developments and structure-activity relationship studies

D Kumar, S Sharma, S Kalra, G Singh… - Current drug …, 2020 - ingentaconnect.com
Indole-based compounds such as … the medicinal and pharmacological importance of the
indole in uplifting human life. In this review, we compiled various reports on indole derivatives

An insight into the medicinal perspective of synthetic analogs of indole: A review

PV Thanikachalam, RK Maurya, V Garg… - … journal of medicinal …, 2019 - Elsevier
… activity relationship of synthesized indole derivatives. … All the reported indole molecules bind
to multiple receptors with … synthetic and medicinal perspective on the development of indole-…

Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives

A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
… topic is introduced for helping the medicinal chemists to understand the perspective of the
context in a … to strategically design diverse novel indole derivatives having different promising …

Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view

N Chadha, O Silakari - European Journal of Medicinal Chemistry, 2017 - Elsevier
… Considering the substitution pattern, potency and mechanism of action of these indole
derivatives, medicinal chemists may design new derivatives with better potency and lesser …

Recent development in indole derivatives as anticancer agent: A mechanistic approach

N Devi, K Kaur, A Biharee… - … Cancer Agents in Medicinal …, 2021 - ingentaconnect.com
… Various mechanisms of indole derivatives in programmed cell death induction have described
Indole-3-carbinol (I3C) (2) is one of the indole derivatives found in vegetables and some …

Therapeutic potential of indole derivatives as anti-HIV agents: A mini-review

Q Chen, C Wu, J Zhu, E Li, Z Xu - Current Topics in Medicinal …, 2022 - ingentaconnect.com
… AIDS/HIV, revealing that indole moiety is a useful template for … ment in indole derivatives,
including indole alkaloids, hybrids… into the medicinal perspective of synthetic analogs of indole: …

Recent progress of bioactivities, mechanisms of action, total synthesis, structural modifications and structure-activity relationships of indole derivatives: a review

T Li, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
… al. gave an insight into the medicinal perspective of synthetic analogs of indole [42]. … indole
derivatives on the C-2 position to obtain target compounds 104a-w [84]. A diversity of indole

An insight into the recent developments in anti-infective potential of indole and associated hybrids

BS Mathada, SB Somappa - Journal of Molecular Structure, 2022 - Elsevier
… class of heteroaromatics in medicinal chemistry, which are … studies of biologically indispensable
indole derivatives. It is … a wide variety of beneficial perspectives such as antibacterial, …

Kinase inhibitor indole derivatives as anticancer agents: a patent review

AK Rathi, R Syed, V Singh, HS Shin… - Recent Patents on Anti …, 2017 - ingentaconnect.com
… The current review elaborates the importance of indole designs as … of indole derivatives
toward specific kinase. Certain patents gathered in the existing review article suggest that indole

The Multi‐Pharmacological Targeted Role of Indole and its Derivatives: A review

B Suliphuldevara Mathada… - …, 2023 - Wiley Online Library
… , medicinal chemistry; the last decade has been onlooker with a multitude of reports on several
indole derivatives … a extensive range of valuable perspectives.The aforesaid molecules …