Medullary thyroid carcinoma in multiple endocrine neoplasia types 2A and 2B

DS O'Riordain, T O'Brien, AL Weaver, H Gharib, ID Hay… - Surgery, 1994 - surgjournal.com
Background. Considerable emphasis has been placed on early diagnosis and surgery for
multiple endocrine neoplasia (MEN)-related medullary thyroid carcinoma (MTC) during the
past two decades. Genetic screening now promises earlier and more accurate diagnosis.
We examine our experience with MTC in MEN 2A and MEN 2B and assess the benefits of
biochemical screening during the past 20 years. Patients and Methods. Seventy-seven
patients undergoing 63 primary total thyroidectomies and 14 reoperative procedures for …
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