… induced maturation by means other than serving as a de novo synthesis and purine nucleotide
utilization help drive meiotic maturation in response to gonadotropin. nucleotide precursor…

… and negative feedback on purine de novo synthesis, … this purine base on meiotic maturation.
The data therefore suggest that nonrnetabolized hypoxanthine IS responsible for the meiotic …

… of purine nucleotide synthetic pathways in gonadotropin-induced meiotic maturation in mouse
… Inhibitory effect of purines in meiotic maturation of denuded oocytes. Mol Reprod Dev 31:…

… role of purines such as hypoxanthine and adenosine in the maintenance of oocyte meiotic
arrest… , a possible action mechanism of purines in oocyte meiotic maturation was investigated. …

… Involvement of purine nucleotide synthetic pathways in gonadotropin-induced meiotic
maturation in mouse cumulus cellenclosed oocytes. Mol Reprod Dev 46:155–167. Downs SM. …

… of the first meiotic division before induction of maturation by the preovulatory LH surge. In
vitro, oocyte maturation occurs spontaneously. The first meiotic arrest is characterized by a …

… follicular development a dramatic flux in purine metabolism … maintain meiotic arrest when
the GMPgenerating arm of the purine … mice have sufficient levels to prevent meiotic resumption. …

… Some experiments were designed to correlate complex and oocyte cAMP with meiotic
maturation. At the end of the 3 hr incubation, oocytes were examined for the presence or absence …

… via PUFAs catabolism for a possible autocrine function to promote meiotic maturation. … for
meiotic maturation, we asked whether elevating PUFA availability disrupts oocyte maturation. …

… For some oocyte maturation experiments, the degree of inhibitory synergism between two
different purines in maintaining meiotic arrest was determined by calculating a synergism …