Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes

CF Fagbohun, SM Downs - Reproduction, 1992 - rep.bioscientifica.com
… that the energy substrate requirements for spontaneous meiotic maturation, maintenance
of meiotic arrest and ligand-induced resumption of meiotic maturation differ significantly in …

Glucose utilization during gonadotropin‐induced meiotic maturation in cumulus cell‐enclosed mouse oocytes

SM Downs, PG Humpherson… - Molecular …, 1996 - Wiley Online Library
required in gonadotropin induction of meiotic maturation, as suppression of lactate
production was not necessarily paralleled by a block in oocyte maturation. Consistent with the …

Energy substrates and the completion of spontaneous meiotic maturation

SM Downs, ED Hudson - Zygote, 2000 - cambridge.org
… how different combinations of pyruvate and glucose affect spontaneous meiotic maturation
of cumulus-cell-enclosed … If glucose can provide the energy required for successful oocyte …

The participation of energy substrates in the control of meiotic maturation in murine oocytes

SM Downs, AM Mastropolo - Developmental biology, 1994 - Elsevier
… The inhibitory effect of glucose on oocyte maturation required cumulus cells and was
accompanied by stimulation of ATP production in oocyte—cumulus cell complexes. We propose …

The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte

SM Downs - Developmental biology, 1995 - Elsevier
… of ATP in the mechanisms controlling maturation. First, it is well … that exerts negative control
on meiotic maturation (cf. Eppig and … Requirement for glucose in ligand-stimulated meiotic

Factors affecting the resumption of meiotic maturation in mammalian oocytes

SM Downs - Theriogenology, 1993 - Elsevier
… GTP?) above the titre required to maintain meiotic arrest when the GMPgenerating arm …
glucose diffusion, to glucose-containing medium prevented glucose uptake as well as the meiotic

Glutamine and the maintenance of meiotic arrest in mouse oocytes: influence of culture medium, glucose, and cumulus cells

SM Downs, A Verhoeven - Molecular Reproduction and …, 2003 - Wiley Online Library
… action of glucose and glutamine on meiotic maturation in dbcAMP… Metabolic coupling and
ligandstimulated meiotic maturation in the … Requirement of glucose in ligandstimulated meiotic

[HTML][HTML] Effects of glucose metabolism during in vitro maturation on cytoplasmic maturation of mouse oocytes

HL Xie, YB Wang, GZ Jiao, DL Kong, Q Li, H Li… - Scientific reports, 2016 - nature.com
… for nuclear maturation, other data indicate that the glucose requirement for meiotic induction
… Furthermore, they arrested meiotic maturation with hypoxanthine, which was found to lower …

Altered meiotic regulation in oocytes from diabetic mice

SA Colton, GM Pieper, SM Downs - Biology of reproduction, 2002 - academic.oup.com
… cumulus cell-enclosed mouse oocytes have indicated that glucose is required for optimal …
of glucose in meiotic regulation. Since glucose can play different roles in the meiotic maturation

Effect of glucose and pyruvate on nuclear and cytoplasmic maturation of porcine oocytes in a chemically defined medium

H Funahashi, T Koike, R Sakai - Theriogenology, 2008 - Elsevier
… species in the glucose requirement for oocyte maturation. In primate oocytes, nuclear … study,
we concluded that glucose played a critical role in resumption of meiosis in porcine oocytes, …