Microphthalmia‐associated transcription factor (MITF) is required but is not sufficient to induce the expression of melanogenic genes

C Gaggioli, R Buscà, P Abbe, JP Ortonne… - Pigment cell …, 2003 - Wiley Online Library
… In addition to MITF, several other transcription factors have been involved in the regulation
of melanogenic gene expression. SOX10, a sex-determining (SRY) related transcription factor

Epigenetic regulation of melanogenesis

S Zhou, H Zeng, J Huang, L Lei, X Tong, S Li… - Ageing research …, 2021 - Elsevier
… MITF is the most important transcription factor in melanogenesis, is the common target of …
transcriptional activator to regulate the expression of several key melanogenesis-related genes, …

[HTML][HTML] Signaling pathways in melanogenesis

SAN D'Mello, GJ Finlay, BC Baguley… - International journal of …, 2016 - mdpi.com
… and transcription factors including the tyrosine kinase receptor KIT, its ligand SCF, as well as
MITF [35]. Genetic, … that signaling from MC1R is the main factor dictating melanogenesis [2]. …

Fifteen‐year quest for microphthalmia‐associated transcription factor target genes

Y Cheli, M Ohanna, R Ballotti… - Pigment cell & …, 2010 - Wiley Online Library
transcription factor (MITF), was initially shown … transcriptional control of Tyrosinase, Tyrp1
and DCT genes, encoding the three enzymes involved in melanin synthesis or melanogenesis. …

[HTML][HTML] Microphthalmia associated transcription factor is a target of the phosphatidylinositol-3-kinase pathway

M Khaled, L Larribere, K Bille, JP Ortonne… - Journal of Investigative …, 2003 - Elsevier
melanogenesis. We thus studied the involvement of this transcription factor in the regulation
of melanogenesis … of Mitf in LY294002-induced melanogenic gene expression (Figure 2a). …

[HTML][HTML] Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation

CB Lin, L Babiarz, F Liebel, M Kizoulis… - Journal of investigative …, 2002 - Elsevier
… Overexpressed microphthalmia-associated transcription factor was … of microphthalmia-associated
transcription factor expression can … -associated transcription factor in melanogenesis. …

Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors

P Wan, Y Hu, L He - Molecular and cellular biochemistry, 2011 - Springer
… -helix (bHLH) transcription factor family that is termed as E proteins. ITF2 is able to regulate
the expression of various tissue-specific genes, such as melanogenic genes, for it can form …

[HTML][HTML] Inhibition of NAT10 suppresses melanogenesis and melanoma growth by attenuating microphthalmia-associated transcription factor (MITF) expression

TI Oh, YM Lee, BO Lim, JH Lim - International journal of molecular …, 2017 - mdpi.com
melanogenesis and melanoma growth. This is the first study to suggest that the pharmacological
or genetic … the downregulation of MITF target genes related to pigmentation. Moreover, …

… effect of Elephantopus mollis HB and K. extract on melanogenesis in B16 murine melanoma cells by downregulating microphthalmia-associated transcription factor …

K Hasegawa, R Furuya, H Mizuno… - Bioscience …, 2010 - jstage.jst.go.jp
related protein 1 (TRP1). Furthermore, the expression level of microphthalmia-associated
transcription factor (MITF), a major transcriptional regulator of genes encoding melanogenic

[HTML][HTML] Ginsenoside Re inhibits melanogenesis and melanoma growth by downregulating microphthalmia-associated transcription factor

SJ Hwang, HJ Bang, HJ Lee - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… of Re on melanogenesis and skin … involved in melanin production. Moreover, Re significantly
reduced the mRNA expression levels of microphthalmia-associated transcription factor (…