[PDF][PDF] Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells

D Tormo, A Chęcińska, D Alonso-Curbelo… - Cancer cell, 2009 - cell.com
… mouse models, we show that melanoma cells retain an innate ability to … melanoma cells
have other sensors of viral pathogens that can be engaged to induce autophagy and cell

[HTML][HTML] Autophagy is a protective mechanism for human melanoma cells under acidic stress

ML Marino, P Pellegrini, G Di Lernia… - Journal of Biological …, 2012 - ASBMB
cells under metabolic stress or subjected to chemotherapy. We investigated the response of
melanoma cells cultured in acidic conditions in terms of survival and autophagy regulation. …

[HTML][HTML] Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

T Tomic, T Botton, M Cerezo, G Robert, F Luciano… - Cell death & …, 2011 - nature.com
autophagic cell death or type II cell death. In our study, several compelling evidences indicate
that metformin induces autophagy in melanoma cells (… is able to induce autophagy in colon …

[HTML][HTML] Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death

JL Armstrong, DS Hill, CS McKee… - Journal of Investigative …, 2015 - Elsevier
autophagy-mediated apoptosis of melanoma cells, suggesting that cytotoxic autophagy
induction … prevented THC-induced autophagy and apoptosis of melanoma cells. However, THC-…

[HTML][HTML] Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF

N Maddodi, W Huang, T Havighurst, KM Kim… - Journal of Investigative …, 2010 - Elsevier
… show that in melanoma cells with oncogenic BRAF (mBRAF), high levels of mBRAF induce
… by rapamycin also induces autophagy and inhibits melanoma cell growth, we treated 451Lu …

[HTML][HTML] Silvestrol induces early autophagy and apoptosis in human melanoma cells

WL Chen, L Pan, AD Kinghorn, SM Swanson… - BMC cancer, 2016 - Springer
induce autophagy, but it does not induce caspase-dependent cell death in human A375
melanoma [34]… These studies support that silvestrol induces both early autophagy and caspase-…

Mechanism of autophagy induction and role of autophagy in antagonizing mitomycin C-induced cell apoptosis in silibinin treated human melanoma A375-S2 cells

Y Jiang, R Yang, H Wang, H Huang, D Wu… - European journal of …, 2011 - Elsevier
induced autophagy in A375-S2 cells. In the present study it was found that silibinin-induced
autophagy … is possible to be a protective mechanism in melanoma cells. And considering our …

[HTML][HTML] Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells

S Tyciakova, V Valova, B Svitkova, M Matuskova - BMC cancer, 2021 - Springer
… the senescence induction also in malignant melanoma cells. Autophagy activation after TNFα
… However, the senescence was not induced in colorectal carcinoma cells HT29hTNFa and …

Zyflamend mediates therapeutic induction of autophagy to apoptosis in melanoma cells

S Ekmekcioglu, C Chattopadhyay*, U Akar*… - Nutrition and …, 2011 - Taylor & Francis
melanoma proliferation. Here, we present that Zyflamend inhibits melanoma growth by regulating
the autophagy–… Our data show that Zyflamend-induced autophagy and apoptosis occur …

Targeting autophagy as a potential therapeutic approach for melanoma therapy

H Liu, Z He, HU Simon - Seminars in cancer biology, 2013 - Elsevier
… to induce autophagy in melanoma cells with hyperactivation of RAS-MEK pathway, although
it induced autophagy in other tumor cell … and activation of autophagy, mTORC1 activity was …