… We speculated that autophagy might participate in the lysosomal … autophagy in melanoma
cells. We first examined the effect of SIRT1 on Beclin 1 acetylation in melanoma cells. We …

… To address this, we first determined whether PLX-4032 induces autophagy, as has been …
In this study, we utilized melanoma cell models to evaluate the therapeutic potential of …

… we show reduced metastatic potential of MEKi‐resistant melanoma cells in response to
combined treatment with trametinib and a novel Vps34 inhibitor PIK‐III,27 while, importantly, …

… melanoma cells display an addiction to autophagy. This is … of autophagy or knockdown of
key autophagy genes (eg Beclin1 and Atg7) in melanoma induces spontaneous melanoma cell …

… While a number of synthetic compounds have been developed, autophagy - modulating …
2 NPs on autophagic vesicle formation in human melanoma A375 cells. The cells were treated …

… on the A‑375 melanoma cell line, and to delineate the … been demonstrated to induce arrest
of the tumor cell cycle and … inhibit proliferation and induce autophagy in liver cancer cells (19), …

… There was an obvious enhancement of red fluorescence, which indicated that testing
samples can induce autophagy on the melanoma cells. In addition, the number of cells was also …

… inducer, this study evaluated the lithium effects on autophagy in B16 melanoma cells to
assess the possibility of inducing autophagic cell death. The number of AV (both initial and …

… therapy was found inducing autophagy in cancer cells, promoting cancer cell proliferation
and … To assess the effects of TanIIA on melanoma cell proliferation, we treated A375 cells with …

… From the screening, we identified several candidates that induced autophagy in B16F1
melanoma cells. Among these candidates, we selected 3′-ODI for further analysis as a potent …