… To the best of our knowledge, it is the first time that Cl10 is reported to induce autophagy
in melanoma cells. Autophagy induction is currently taken to represent a novel therapeutic …

… Beclin-1 is associated with graveoline-induced autophagy To confirm whether Beclin-1
played any role in inducing autophagy in A375 cells upon graveoline administration, expression …

… with the degradation property of autophagy, we have demonstrated that targeting BECN1
prevented the degradation of NK-derived GranzymeB (GzmB) in hypoxic melanoma cells, and …

… inhibit B16 melanoma cell growth by inducing autophagy in a C57BL/6 mouse model.
Melanoma is a … Melanoma is difficult to diagnose in the early stages and is often fatal once it has …

… Autophagy could be triggered via several signaling pathways. AMPK activation … autophagy
signaling [1] . AMPK not only directly phosphorylates and activates ULK1 to induce autophagy…

… induction of apoptosis and autophagy with AIII are not well documented. The effects of AIII
on malignant melanoma cells … We examined the effect of 3-MA on AIII-induced autophagy by …

… autophagic response seems to be an essential pro-survival mechanism that not only allows
melanoma cells to thrive … Of note, ER stress induced autophagy can also occur in an eIF2α-…

… autophagic flux and induces autophagy via inhibition of the mTOR pathway in BRAFV600E
melanoma cells… underlying LGX818-activated autophagy in melanoma cells, we examined …

… Characteristic features of early and late stages of autophagy were used to determine the
ability of fenretinide and bortezomib to induce autophagy in 3 human melanoma cell lines. …

… necessary for induction of autophagy that delays apoptosis in melanoma cells under nutrient
… Indeed, Noxa is responsible for oncogenic RAS-induced autophagy through displacing Mcl-…