… cells can also attract immune cells. In this study, we show in isogenic murine melanomas
that natural Stat3 activity is associated with tumor growth and reduction of T cell infiltration. …

… might be responsible for Stat3 activation in melanoma cells, we … on Stat3 DNA-binding
activity in melanoma cell lines. To assess if JAKs are involved in Stat3 activation in melanoma cells…

… We found that STAT3 activity increases melanoma invasiveness and is required for
active melanogenesis by regulating tyrosinase gene expression and enzyme activity. …

… In the present study, we found that blockade of Stat3 activity in brain metastatic melanoma
cells suppressed angiogenesis in brain metastases in nude mice. The inhibition of brain …

… STAT3 phosphorylation in the two melanoma cell lines that exhibited marked changes in
MAPK/PI3K activities revealed a higher basal level of Ser 727 phosphorylation in LU1205 cells …

… pS-STAT3 and the cell survival activity of melanoma cells was … effects of U0126 on cell survival
activity of melanoma cells were … the cell survival activity of all the four melanoma cell lines …

… STAT3 signaling pathway in melanoma cells by … the STAT3 signaling pathway in the
anti-melanoma activities of quercetin. Our experiments shows that quercetin inhibits melanoma cells …

… We further show that downregulation of STAT3 activity or upstream RTKs prevent the … We
observed that confluence in our melanoma cells increases STAT3 phosphorylation, but the …

… M14 melanoma cells showed that the protein ERp57 (endoplasmic reticulum protein 57)
binds to DNA in the proximity of STAT3 in a subset of STAT3-regulated genes. In the same cells, …

… specifically inhibit the STAT3 signaling pathway to induce apoptosis in melanoma cells. …
the biologic activity of the FLLL32 curcumin analog on human melanoma and immune effector …