… categorized into this group of peroxins. We demonstrated in the present study that the
membrane assembly process(es) involving integration of Pex3p is temporally differentiated from …

… peroxins required for both membrane assembly and matrix protein import are identified: ten
mammalian pathogenic peroxins … , Pex3p, Pex16p and Pex19p are categorized as a peroxin …

… that Pex16p functions in peroxisome membrane assembly, more likely upstream of Pex3p. …
The membrane-assembly step is initiated by at least three peroxins, Pex3p, Pex16p, and …

… assembly, division, and inheritance are named peroxins (encoded by PEX genes). Over a
dozen peroxins … Dysfunction of peroxins causes fatal human peroxisome biogenesis disorders …

… –Pex19p complexes, using the semi-intact cells that had been ectopically and transiently
expressed with EGFP-fused or HA-tagged PMPs including membrane-integrated peroxins. To …

… role of Pex3p and Pex19p – two evolutionarily conserved peroxins – in PMP biogenesis. …
The peroxin Pex3p has been identified as a peroxisomal membrane protein in yeasts [7], [51…

… membrane protein required for peroxisome formation. It is inserted into the ER membrane
and … By constructing chimeras between Pex3 and the type III ER membrane protein Sec66, we …

… About 35 PEROXIN mutants are … membranes (containing PMPs) but defective in the import
of some or most matrix constituents. However, only mutations in genes encoding two peroxins …

… Pex19 is an acidic peroxin that associates with membranes through its C‐terminal farnesyl
tail, and serves as a receptor and chaperone for Class I PMPs, recognizing and binding the …

… For instance, studies on mammalian PMPs suggested that several model substrates,
including membrane peroxins, Pex3p and Pex16p, are targeted to peroxisomes either directly or …