[HTML][HTML] Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells
JK Millet, GR Whittaker - Virology, 2018 - Elsevier
… In this review, we use SARS-CoV as model for studying the mechanism of coronavirus-membrane
fusion. We aim to give an overview of the entry pathway of SARS-CoV and connect …
fusion. We aim to give an overview of the entry pathway of SARS-CoV and connect …
Spike protein mediated membrane fusion during SARS‐CoV‐2 infection
X Li, H Yuan, X Li, H Wang - Journal of Medical Virology, 2023 - Wiley Online Library
… cells, leading to cell membrane fusion and the formation of … membrane fusion. Here in
this review, we will summarize our current understanding of spike-mediated membrane fusion…
this review, we will summarize our current understanding of spike-mediated membrane fusion…
Design of potent membrane fusion inhibitors against SARS-CoV-2, an emerging coronavirus with high fusogenic activity
Y Zhu, D Yu, H Yan, H Chong, Y He - Journal of virology, 2020 - Am Soc Microbiol
… receptor binding and membrane fusion, thus … SARS-CoV-2 S protein has evolved a high
level of activity to mediate cell-cell fusion, significantly differing from the S protein of SARS-CoV …
level of activity to mediate cell-cell fusion, significantly differing from the S protein of SARS-CoV …
Coronavirus membrane fusion mechanism offers a potential target for antiviral development
… exists between the SARS-CoV and MERS-CoV S2 membrane fusion domains, there are
key differences in their fusion mechanism for plasma membrane entry. For one, MERS-CoV S …
key differences in their fusion mechanism for plasma membrane entry. For one, MERS-CoV S …
Binding of SARS-CoV-2 fusion peptide to host endosome and plasma membrane
… the two membranes together. … SARS-CoV-2 FP: to attach quickly to cellular membranes and
to form an anchor strong enough to withstand the mechanical force during membrane fusion. …
to form an anchor strong enough to withstand the mechanical force during membrane fusion. …
In situ architecture and membrane fusion of SARS-CoV-2 Delta variant
Y Song, H Yao, N Wu, J Xu, Z Zhang… - Proceedings of the …, 2023 - National Acad Sciences
… of ongoing homotypic fusion between Delta … membrane fusion were interpreted. These
results provided molecular insights into membrane remodeling leading to SARS-CoV-2 fusion. …
results provided molecular insights into membrane remodeling leading to SARS-CoV-2 fusion. …
Computational insight into the mechanism of SARS-CoV-2 membrane fusion
S Borkotoky, D Dey, M Banerjee - Journal of Chemical Information …, 2021 - ACS Publications
… SARS-CoV-2 Spike required for triggering membrane fusion, … fusion peptides between the
opposing POPC membranes in … (i) fusion peptides are in contact with both membranes and (ii) …
opposing POPC membranes in … (i) fusion peptides are in contact with both membranes and (ii) …
[HTML][HTML] Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion
… fusion of the virus and cell membranes to release the virus genome into the cell. Both receptor
binding and membrane fusion … As with other class-I membrane-fusion proteins, the spike …
binding and membrane fusion … As with other class-I membrane-fusion proteins, the spike …
Identifying distinct structural features of the SARS-CoV-2 spike protein fusion domain essential for membrane interaction
D Birtles, J Lee - Biochemistry, 2021 - ACS Publications
The SARS-CoV-2 spike protein is the primary antigenic determinant of the virus and has … ,
yet the process of membrane fusion remains poorly understood. The fusion domain (FD) of …
yet the process of membrane fusion remains poorly understood. The fusion domain (FD) of …
Mechanistic insights of host cell fusion of SARS-CoV-1 and SARS-CoV-2 from atomic resolution structure and membrane dynamics
H Chakraborty, S Bhattacharjya - Biophysical Chemistry, 2020 - Elsevier
… fusion mechanism of SARS-CoV-1 from available atomic resolution structures and membrane
binding of fusion … model of membrane fusion or stalk model proposes that the fusion starts …
binding of fusion … model of membrane fusion or stalk model proposes that the fusion starts …
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