34 天前 - … cell compartment, we now conclude that T cell-intrinsic PKD3 is a fine-tuner of central
memory T cell as well as CD8 … regulation of T cell fate on molecular level. Previous studies …

95 天前 - … memory CD8 T cells, our results differed sharply in regard to the influence of Opa1
on effector-fated, not memory-fated, T cell expansion. This predominant influence on effector …

138 天前 - … and interestingly, they are also distinct from effector and memory CD8+ T cells …
Thus, it appears that the stem-like CD8+ T cell fate commitment is agnostic to antigen outcome, …

169 天前 - … memory CD8+ T cells can undergo ACD and exhibit “stem-like” properties, as opposed
to terminally differentiated effector cells (… terms of CD8+ T cell fate. Based on our results, …

203 天前 - … cell receptor (TCR), co-stimulatory receptors, and cytokine receptors each influence
CD8 T cell fate. … ) caused naïve and central memory CD8 T cells to accumulate in peripheral …

208 天前 - … naïve CD8 T cells is to proliferate and differentiate into effector and memory phenotypes
… Thus, we followed in vivo T ARCH dynamics and cell fate of virus-specific CD8 T cells …

226 天前 - … CD8 T cell fate through a multifaceted mechanism. We observed that hAMSCs are
able to impact the metabolism of naive CD8 … The formation of an adaptive T cell memory …

240 天前 - … Tfr and CD4 Tfc cells were exclusive to FL, whereas the prevalence and gene
expression profiles of CD8 Tfc cells varied across cancers. Tnfr cells were marked by abundant …

241 天前 - … T cell activation and differentiation from naïve states to effector states, highlighting
the importance of chromatin interactions in T cell fate … that exhausted CD8 T cells may have …

264 天前 - … Next, we aimed to characterize the transcriptome of NS3 968 -specific long-lived
memory CD8 T cells residing in the liver and spleen of mice >2 months after virus clearance. …