… Memory CD8 T cells are an important component of protective immunity against viral
infections… that occurs during a CD8 T-cell response to viral infection. Dramatic cellular changes …

… chronic LCMV infection this normal memory CD8 T cell differentiation pathway does not
proceed efficiently and virus-specific CD8 T cells fail to acquire the cardinal memory T cell …

… chronic viral infection precludes the development of long-lived antigen-independent
memory CD8 T cells and might even result in severe dysfunction of virus-specific CD8 T cells. …

… of memory cells specific to previously encountered pathogens. In this study, the patterns and
significance of virus-induced memory CD8 … , vaccinia) viruses and subsequently challenged …

… Our studies show that each virus infection is characterized by enrichments of CD8 + T cells
with different phenotypes—consistent with distinct stages of differentiation—during chronic …

… memory is generated in response to virus infections and how these cells respond when the
host is infected again by similar or different viruses. … of virus-specific memory CD8 T cells was …

… 18 viral proteins. In contrast, we show here that the CD8 T cell response in chronically infected
mice … + T cell responses from primary to persistent phases of Epstein-Barr virus infection. …

… memory CD8 T cells generated in response to infection. Specifically, we will discuss (1) current
subset classifications of memory CD8 T … viral infection (69, 70). Changes observed in late …

… are functional for life, despite the presence of persistent viral infection. … the memory CD8 T
cells remain functional up to 1 y pi (27). In this study, we analyzed how the gB-8p memory CD8 …

… Our studies reveal that memory CD8 T cells enhance RSV clearance similar to other viral
infections, but are unique in that they mediate severe immunopathology caused by the …