Molecular regulation of effector and memory T cell differentiation

JT Chang, EJ Wherry, AW Goldrath - Nature immunology, 2014 - nature.com
… four distinct subsets of memory T lymphocytes: central memory T cells (T CM cells), … memory
T cells (T EM cells), tissue-resident memory T cells (T RM cells) and stem memory T cells

The who's who of Tcell differentiation: human memory Tcell subsets

YD Mahnke, TM Brodie, F Sallusto… - European journal of …, 2013 - Wiley Online Library
… This review illustrates the memory T-cell compartment's complexity according to the … discrete
memory subsets. We propose a unified model of human memory T-cell differentiation along …

Distinct regulation of effector and memory Tcell differentiation

A Kallies - Immunology and cell biology, 2008 - Wiley Online Library
… ) expression as a hallmark for memory T cells and their precursors has … memory T-cell
differentiation. This has also led to the finding that under most if not all conditions memory T cells

Effector and memory T-cell differentiation: implications for vaccine development

SM Kaech, EJ Wherry, R Ahmed - Nature Reviews Immunology, 2002 - nature.com
memory T- and B-cell development, this review will focus on the formation of effector and
memory T cells, … for the development of these cells. We will discuss primarily the formation of …

Transcriptional control of effector and memory CD8+ T cell differentiation

SM Kaech, W Cui - Nature Reviews Immunology, 2012 - nature.com
… The expression or activity of counter-regulatory transcription factors functions in a graded
manner to regulate effector and memory T cell differentiation. Such transcription factor pairs …

Memory CD8+ T cell differentiation

JJ Obar, L Lefrançois - Annals of the New York Academy of …, 2010 - Wiley Online Library
… the development of distinct effector and memory CD8 + T cell sublineages. In this review …
T cell response and highlight the elements regulating the differentiation of effector and memory

Tcell memory differentiation: insights from transcriptional signatures and epigenetics

B Youngblood, JS Hale, R Ahmed - Immunology, 2013 - Wiley Online Library
… antigen-specific T cells undergo … differentiation to the effector and memory phases of the
immune response. The changes in cell phenotype that accompany memory T-cell differentiation

Epigenomics of T cell activation, differentiation, and memory

S Cuddapah, A Barski, K Zhao - Current opinion in immunology, 2010 - Elsevier
… On the other hand, memory T cells are poised and do not require … in T cell differentiation
from naïve to memory cells, the short-term activation and effector functions of memory cells do …

CD4+ memory T cells: functional differentiation and homeostasis

B Stockinger, C Bourgeois… - Immunological reviews, 2006 - Wiley Online Library
T cells that fully differentiated into IFN-γ-secreting cells appear to have a lower potential to
develop into memory T cells … IFN-γ positive or negative CD4 + T cells, identified by a cytokine …

Molecular and functional profiling of memory CD8 T cell differentiation

SM Kaech, S Hemby, E Kersh, R Ahmed - Cell, 2002 - cell.com
… How and when memory T cells form during an immune response are … memory CD8 T cell
differentiation. First, we have tried to uncover molecular mechanisms involved in memory cell