Thrombin generation and atherothrombosis: what does the evidence indicate?

H Ten Cate, HC Hemker - Journal of the American Heart …, 2016 - Am Heart Assoc
thrombin is a critical determinant of hemostasis and according to Hemker’s first law, a low
amount of thrombin … is the relation between thrombin generation and clinical manifestations of …

Thrombin generation and venous thromboembolism

S Eichinger - Hämostaseologie, 2008 - thieme-connect.com
Thrombin generation is increased in patients at risk of thrombosis including those with
antithrombin … Theriskof recurrent venous thromboembolism in men and women. N Engl J Med …

Thrombin generation is associated with ischemic stroke at a young age

SJ Donkel, K Pater, FWG Leebeek, DWJ Dippel… - Thrombosis …, 2021 - Elsevier
… in elderly patients and literature on thrombin generation in young IS patients is … thrombin
generation and a first IS or TIA in patients aged ≤45 years in men and ≤55 years in women. …

Thrombin generation in patients with a bleeding tendency of unknown origin

C Ay, J Haselböck, C Laczkovics, S Koder… - Annals of …, 2011 - Springer
… 3,414 [3,045–3,750] nM thrombin, p = 0.673). In conclusion, the thrombin generation potential
… Also, in separate analyses for women and men, no difference in thrombin generation was …

Thrombin generation and activated protein C resistance in the absence of factor V Leiden correlates with the risk of recurrent venous thromboembolism in women …

K Sonnevi, SN Tchaikovski… - Thrombosis and …, 2011 - thieme-connect.com
… ● We find that he thrombin generation assay is useful to evaluate women at risk of recurrence
… -based test predicts for venous thrombosis in men and women. Br J Haematol 2003; 122: …

Sex differences in Thrombin Generation in patients with Acute ischemic Stroke

S Falcione, E Spronk, D Munsterman, T Joy… - Translational Stroke …, 2023 - Springer
Women also derive greater 90-day benefit from treatment with tissue … to men suggesting
increased efficacy in women [3]. However, one study reported that compared to men, women

Thrombin generation test as a marker for high risk venous thrombosis pregnancies

BS Joly, B Sudrié-Arnaud, V Barbay, JY Borg… - Journal of thrombosis …, 2018 - Springer
… Our objective was to investigate the usefulness of thrombin generation test (TGT) as a
marker to predict the risk of thrombosis in high risk venous thrombosis (HRVT) pregnancies …

Thrombin generation, a function test of the haemostaticthrombotic system

HC Hemker, R Al Dieri, E De Smedt… - Thrombosis and …, 2006 - thieme-connect.com
… of the plasmatic thrombin generatingthrombin generation in arterial thrombotic disease
remains enigmatic. We surmise that much can be learned from the study of thrombin generation

Factor Xa generation by computational modeling: an additional discriminator to thrombin generation evaluation

KE Brummel-Ziedins, T Orfeo, M Gissel, KG Mann… - PloS one, 2012 - journals.plos.org
generation in individuals might add to our understanding of variations in thrombin generation
… are aware of that compares fXa generation to thrombin generation in the same population …

Thrombin generation assessed as endogenous thrombin potential in patients with hyper-or hypo-coagulability

V Chantarangkul, M Clerici, C Bressi, PL Giesen… - …, 2003 - haematologica.org
… time to peak and the endogenous thrombin potential (ETP). This last is the area under the
thrombin generation curve and represents the total amount of thrombin formed over time, after …