Mechanisms of action of estrogen receptors in vascular cells: relevance for menopause and aging

T Simoncini - Climacteric, 2009 - Taylor & Francis
… In fact, estrogen triggers a number of rapid actions in vascular cells, inducing vasodilatation,
exerting anti-inflammatory activity, regulating vascular cell growth and migration as well as …

Vascular aging across the menopause transition in healthy women

KL Moreau, KL Hildreth - Advances in vascular medicine, 2014 - Wiley Online Library
… The arterial wall is composed of vascular smooth muscle cells which vasodilate and
vasoconstrict in response to a number of circulating and local vasoactive mediators including those …

Intersection between gonadal function and vascular aging in women

KL Moreau - Journal of Applied Physiology, 2018 - journals.physiology.org
… with the menopausal transition on vascular aging in women and … intersection between gonadal
function and vascular aging. … The vascular endothelium is a single cell layer that lines the …

Coronary artery disease in aging women: a menopause of endothelial progenitor cells?

R Hutter, JJ Badimon, V Fuster, J Narula - Medical Clinics, 2012 - medical.theclinics.com
… The peripheral blood EPCs act as a circulating pool of cells capable of maintaining the
critical homeostasis of the luminal endothelial vascular surface. In addition, EPCs are mobilized …

Estrogenic compounds, estrogen receptors and vascular cell signaling in the aging blood vessels

DA Smiley, RA Khalil - Current medicinal chemistry, 2009 - ingentaconnect.com
… in 1942 for treatment of menopausal symptoms such as hot … -menopausal women (PreMW)
than in men of the same age, … in plasma levels of estrogen during menopause [5]. In effect, …

Estrogen receptor and vascular aging

M Davezac, M Buscato, R Zahreddine, P Lacolley… - … in aging, 2021 - frontiersin.org
menopause (age <40 years) or early menopause (age 40–44 … compared to women who
had menopause at age 50–51 (… in the different vascular cell types during aging and how …

The menopause and aging, a comparative perspective

CE Finch - The Journal of steroid biochemistry and molecular …, 2014 - Elsevier
… The neuroendocrinology of menopause is reviewed from a comparative perspective, with …
criteria (Stages of Reproductive Aging Workshop). Ovarian cell loss begins prenatally in all …

Vascular aging in women: is estrogen the fountain of youth?

S Novella, AP Dantas, G Segarra, P Medina… - Frontiers in …, 2012 - frontiersin.org
menopause and aging contribute jointly to vascular aging and how estrogen modulates
vascular … functioning of vascular cells, other molecules crucial to control of vascular function are …

[HTML][HTML] Cardiovascular changes in menopause

AR Nair, AJ Pillai, N Nair - Current cardiology reviews, 2021 - ncbi.nlm.nih.gov
… Endothelial dysfunction is a contributor to vascular aging and a key initiator in the … oxide
(NO) by vascular endothelium, which then diffuses into vascular smooth muscle cells, causing its …

Tissue-specific effects of loss of estrogen during menopause and aging

K Wend, P Wend, SA Krum - Frontiers in endocrinology, 2012 - frontiersin.org
… heart, but also the vasculature. ERα and ERβ are both expressed in vascular endothelial
cells and vascular smooth muscle cells. E2 regulates many genes in these cell types, such as …