Gut microbiota, kynurenine pathway and mental disorders–Review

M Więdłocha, P Marcinowicz… - Progress in Neuro …, 2021 - Elsevier
… the kynurenine pathway taken into special account. Up to date study results on specific
psychiatric disorders related to the above interactions have also been presented. (See Fig. 1, Fig. …

The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies

W Marx, AJ McGuinness, T Rocks, A Ruusunen… - Molecular …, 2021 - nature.com
… of tryptophan along the kynurenine pathway and its involvement in mental disorders is an …
differences in kynurenine metabolites in major depressive disorder (MDD), bipolar disorder (…

The kynurenine pathway in bipolar disorder: a meta-analysis on the peripheral blood levels of tryptophan and related metabolites

F Bartoli, B Misiak, T Callovini, D Cavaleri… - Molecular …, 2021 - nature.com
mental disorders. In order to improve the consistency and comparability of data, we excluded
studies that measured KP components in other biological tissues (eg, cerebrospinal fluid). …

[HTML][HTML] Kynurenine pathway metabolites and suicidality

EY Bryleva, L Brundin - Neuropharmacology, 2017 - Elsevier
… Inflammation also causes activation of the kynurenine pathway of … dysregulation of the
enzymes in the kynurenine pathway may contribute to the … Kynurenine pathway and inflammation …

The metabolic factor kynurenic acid of kynurenine pathway predicts major depressive disorder

H Liu, L Ding, H Zhang, D Mellor, H Wu, D Zhao… - Frontiers in …, 2018 - frontiersin.org
… Major depressive disorder (MDD) is a serious mental disorder with high rates of morbidity,
recurrence, and disability (1–3) that is associated with genetic factors, psychological factors …

[HTML][HTML] Kynurenine pathway of tryptophan metabolism in neuropsychiatric disorders: pathophysiologic and therapeutic considerations

A Muneer - Clinical Psychopharmacology and Neuroscience, 2020 - ncbi.nlm.nih.gov
… known about the neurobiology of mental disorders, but now this … pathway, known as the
kynurenine pathway (KP) is involved in the pathophysiology of principal psychiatric disorders [1]. …

Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies

D Arnone, S Saraykar, H Salem, AL Teixeira… - Neuroscience & …, 2018 - Elsevier
… between activation of the kynurenine pathway and mood disorders by systematically …
kynurenine metabolites (tryptophan, kynurenine, kynurenic acid, quinolinic acid, ratio of kynurenine

The kynurenine pathway: a finger in every pie

J Savitz - Molecular psychiatry, 2020 - nature.com
… However, many of its metabolites, collectively termed “kynurenines”, are … disorder, this
review provides an overview of the impact of the kynurenines on several physiological pathways

Kynurenine pathway in depression: A systematic review and meta-analysis

K Ogyu, K Kubo, Y Noda, Y Iwata, S Tsugawa… - Neuroscience & …, 2018 - Elsevier
… Differences in metabolite levels of the kynurenine pathway between patients and controls …
the data that examined metabolites of the kynurenine pathway. If the identified articles did not …

Role of kynurenine metabolism pathway activation in major depressive disorders

J Savitz - Inflammation-associated depression: Evidence …, 2017 - Springer
… immuno-regulatory pathway, the kynurenine pathway which is … papers showed that kynurenine
pathway metabolites appear … the activation of the kynurenine pathway is genetically or …