Mesenchymal stem cells in kidney inflammation and repair

AF Wise, SD Ricardo - Nephrology, 2012 - Wiley Online Library
… the features of mesenchymal stem cells and the factors they release that protect against
kidney injury; the mechanisms of homing and engraftment to sites of inflammation; and further …

[HTML][HTML] Mesenchymal stem cell–derived extracellular vesicles attenuate kidney inflammation

A Eirin, XY Zhu, AS Puranik, H Tang, KA McGurren… - Kidney international, 2017 - Elsevier
… In this study, MetS + RAS–induced renal inflammation was associated with increased …
kidney injury and fibrosis, and represents a common pathway to end-stage renal disease. …

Early modulation of inflammation by mesenchymal stem cell after acute kidney injury

P Semedo, CG Palasio, CD Oliveira, CQ Feitoza… - International …, 2009 - Elsevier
… All IRI responses are somehow altered by administration of exogenously mesenchymal
stem cells (MSC), also named multipotent stromal cell. Several groups have showed …

Potential and therapeutic efficacy of cell-based therapy using mesenchymal stem cells for acute/chronic kidney disease

CW Yun, SH Lee - International journal of molecular sciences, 2019 - mdpi.com
… disease model, the administration of MSC-derived EVs improves renal inflammation by
decreasing the levels of inflammatory cytokines, such as TNF-α, IL-6, and IL-1-β. Moreover, in …

Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

Y Shi, Y Wang, Q Li, K Liu, J Hou, C Shao… - Nature Reviews …, 2018 - nature.com
… as mesenchymal stromal cells) have attracted much attention for their ability to regulate
inflammatory … b | Infused MSCs can suppress renal inflammation directly or indirectly through the …

Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the …

B Liu, F Ding, D Hu, Y Zhou, C Long, L Shen… - Stem cell research & …, 2018 - Springer
… by infiltration of interstitial inflammatory cells and release of inflammatory mediators, …
mesenchymal stem cell (hucMSC) conditioned medium (CM) on renal tubulointerstitial inflammation

Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction

YT Chen, CK Sun, YC Lin, LT Chang, YL Chen… - Journal of translational …, 2011 - Springer
… We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs) protect the
kidney against oxidative stress and inflammatory stimuli in rat during renal IR injury. …

Mesenchymal stem cells—potential applications in kidney diseases

B Bochon, M Kozubska, G Surygała… - International journal of …, 2019 - mdpi.com
inflammation and initiating tissue regeneration. Owing to these properties, mesenchymal stem
cells (… research in the settings of kidney diseases in which inflammation plays the key role. …

[HTML][HTML] Bone marrow-derived mesenchymal stem cells transplantation ameliorates renal injury through anti-fibrotic and anti-inflammatory effects in chronic …

A Almeida, R Lira, M Oliveira, M Martins, Y Azevedo… - biomedical …, 2022 - Elsevier
… fibrosis is an underlying pathological process of chronic kidney disease (CKD) … mesenchymal
stem cells (MSC) in the remodeling of fibrotic kidney parenchyma in the two kidneys-one …

Mesenchymal stem cells in acute kidney injury

BD Humphreys, JV Bonventre - Annu. Rev. Med., 2008 - annualreviews.org
… BM-derived inflammatory cells home to injured kidney, recent studies have suggested that
BMDCs directly participate in renal injury and repair. Mesenchymal stem cells in particular …