Issues in the selection of a summary statistic for metaanalysis of clinical trials with binary outcomes

JJ Deeks - Statistics in medicine, 2002 - Wiley Online Library
Metaanalysis of binary data involves the computation of a weighted average of summary
statistics calculated for each trial. The selection of the appropriate summary statistic is a …

Systematic review of methods for individual patient data meta-analysis with binary outcomes

D Thomas, S Radji, A Benedetti - BMC medical research methodology, 2014 - Springer
… the use of binary outcomes in assessing the effects of health care problems has increased,
with random effects logistic regression the most common method of analysis. Methods are …

A comparison of methods for metaanalysis of a small number of studies with binary outcomes

T Mathes, O Kuss - Research synthesis methods, 2018 - Wiley Online Library
metaanalyses to best mirror real‐life situations. We show that valid methods for metaanalysis
In random effects situations, the beta‐binominal model performed best for metaanalysis

A multilevel model framework for metaanalysis of clinical trials with binary outcomes

RM Turner, RZ Omar, M Yang, H Goldstein… - Statistics in …, 2000 - Wiley Online Library
analysis tool for hierarchical data [16]. In this paper we put existing methods for meta-analysis
of two-arm clinical trials with binary outcomes … At present, the majority of meta-analyses are …

Quantifying heterogeneity in individual participant data meta-analysis with binary outcomes

B Chen, A Benedetti - Systematic reviews, 2017 - Springer
… A review of statistical methods used in IPD-MA of binary outcomes found that most do not …
quantifying heterogeneity in IPD-MA of binary outcomes analyzed via the one-stage approach. …

A method for the metaanalysis of mutually exclusive binary outcomes

TA Trikalinos, I Olkin - Statistics in Medicine, 2008 - Wiley Online Library
meta-analyses, and also by taking the between-outcome correlation into account. We argue
… mutually exclusive outcomes in the meta-analyses of binary data are optimally analyzed in …

Metaanalysis of a binary outcome using individual participant data and aggregate data

RD Riley, EW Steyerberg - Research Synthesis Methods, 2010 - Wiley Online Library
… In this paper, we develop meta-analysis models that synthesize a binary outcome from
health-care studies while accounting for participant-level covariates. In particular, we show how to …

A Bayesian network meta-analysis for binary outcome: how to do it

T Greco, G Landoni, G Biondi-Zoccai… - … methods in medical …, 2016 - journals.sagepub.com
meta-analysis (NMA), particularly focusing on its application to randomised controlled trials
with a binary outcome of … to collect study data, structure the analytical network and specify the …

A refined method for the metaanalysis of controlled clinical trials with binary outcome

J Hartung, G Knapp - Statistics in medicine, 2001 - Wiley Online Library
OUTCOME MEASURES FOR BINARY DATA … of the three different outcome measures
for binary data, which we also use in the simulation study. The outcome measures are the risk …

High statistical heterogeneity is more frequent in meta-analysis of continuous than binary outcomes

AC Alba, PE Alexander, J Chang, J MacIsaac… - Journal of clinical …, 2016 - Elsevier
… of I 2 in meta-analyses on binary outcomes showed similar results to those reported in this
article: almost 50% of meta-analysis on binary outcomes show heterogeneity easily explained …