Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis
D Posthuma - Molecular psychiatry, 2018 - research.vu.nl
… the signal most strongly supported in this metaanalysis (best was rs9952159, P = 4.2 ×
10 … Among the other genes of interest, signals in or near PTPRD, which was previously …
10 … Among the other genes of interest, signals in or near PTPRD, which was previously …
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes
…, MEta-analysis of type 2 DIabetes in African … - … genetics, 2014 - journals.plos.org
… meta-analysis of 17 GWAS in 8,284 cases and 15,543 controls to explore the genetic architecture
of … in other populations due to differential genetic architecture across populations. Our …
of … in other populations due to differential genetic architecture across populations. Our …
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Approaches exploiting trait distribution extremes may be used to identify loci associated
with common traits, but it is unknown whether these loci are generalizable to the broader …
with common traits, but it is unknown whether these loci are generalizable to the broader …
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
… genetic architecture … Genetic architecture and risk scores By increasing the number of
European-origin psoriasis susceptibility loci to 63, we were able to explore the genetic architecture …
European-origin psoriasis susceptibility loci to 63, we were able to explore the genetic architecture …
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
Genome-wide association studies (GWASs) have identified hundreds of susceptibility genes,
including shared associations across clinically distinct autoimmune diseases. We …
including shared associations across clinically distinct autoimmune diseases. We …
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
DIAbetes Genetics Replication And Meta-analysis … - … genetics, 2014 - nature.com
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we
aggregated published meta-analyses of genome-wide association studies (GWAS), including …
aggregated published meta-analyses of genome-wide association studies (GWAS), including …
Rice root genetic architecture: meta-analysis from a drought QTL database
B Courtois, N Ahmadi, F Khowaja, AH Price, JF Rami… - Rice, 2009 - Springer
… Following the development of molecular genetic approaches, the genetic architecture of
the rice root system has been extensively studied by teams interested in improving drought …
the rice root system has been extensively studied by teams interested in improving drought …
Revealing the genetic architecture of FHB resistance in hexaploid wheat (Triticum aestivum L.) by QTL meta-analysis
M Löffler, CC Schön, T Miedaner - Molecular Breeding, 2009 - Springer
Fusarium head blight (FHB) in wheat results in reduced yield and quality and in accumulation
of mycotoxins. The objective of this study was to identify genomic regions in wheat …
of mycotoxins. The objective of this study was to identify genomic regions in wheat …
Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
… Our data demonstrate that the genetic architecture does not differ based on the diagnostic
criteria used for PCOS. We also demonstrate a genetic pathway shared with male pattern …
criteria used for PCOS. We also demonstrate a genetic pathway shared with male pattern …
Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis
JJ Tielbeek, E Uffelmann, BS Williams… - Molecular …, 2022 - nature.com
… estimates concerning the genetic overlap between personality and ASB. It seems worthwhile
to mention again here that partially overlapping genetic architectures do not provide causal …
to mention again here that partially overlapping genetic architectures do not provide causal …
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